Results 101 to 110 of about 9,680 (207)

The association between sleep disturbance and stimulant use: A cross‐lagged examination

Addiction, Volume 121, Issue 8, Page 2116-2126, August 2026.
Abstract Background and aims Sleep disruptions increase the risk of substance misuse. Substance use—especially stimulants—can increase acute and chronic sleep dysfunction. This study aimed to estimate the associations between sleep disturbance and stimulant use over time among participants with stimulant use disorder (StUD).
Viviana E. Horigian, Renae D. Schmidt, Daniel J. Feaster, Rui Duan, Sophia T. Gonzalez, Kathryn Hefner, Dikla Shmueli‐Blumberg, Ashley Vena, Landhing M. Moran, Chloe A. DiCamillo, Shirin Shafazand, Susan Tross, Judith Feinberg   +12 more
wiley   +1 more source

Therapeutic intervention with sinomenine and irisin to preserve cardiac function after ischaemia–reperfusion injury

Experimental Physiology, Volume 111, Issue 8, Page 3557-3569, 1 August 2026.
Abstract Despite advancements in reperfusion therapy, myocardial ischaemia–reperfusion (IR) injury remains a major clinical challenge. This study investigated whether a novel dual‐target pre‐conditioning strategy using sinomenine and irisin could enhance myocardial resistance against IR injury. Ninety male Sprague–Dawley rats were utilized.
Lianjun Wu, Sining Bi, Amany Belal, Zhuzhu Liu   +3 more
wiley   +1 more source

Nlrp2 deletion ameliorates kidney damage in a mouse model of cystinosis

Frontiers in Immunology
Cystinosis is a rare autosomal recessive disorder caused by mutations in the CTNS gene that encodes cystinosin, a ubiquitous lysosomal cystine/H+ antiporter.
Marianna Nicoletta Rossi, Marianna Nicoletta Rossi, Valentina Matteo, Francesca Diomedi-Camassei, Ester De Leo, Olivier Devuyst, Mohamed Lamkanfi, Ivan Caiello, Elena Loricchio, Francesco Bellomo, Anna Taranta, Francesco Emma, Fabrizio De Benedetti, Giusi Prencipe   +13 more
doaj   +1 more source

YLubell/SEA-CTN: surveillance-poct

, 2018
Accounting for aetiology: can regional surveillance data alongside host biomarker-guided antibiotic therapy improve treatment of febrile illness in remote settings? Authors Chandna A1,2, White LJ1,3, Pongvongsa T4, Mayxay M3,4,5, Newton PN3,4, Day NPJ1,3, Lubell Y1,3* Mahidol-Oxford Tropical Medicine Research Unit (MORU), Bangkok, Thailand ...
openaire   +2 more sources

CTN Multiple Comparisons Procedures SOP

, 2016
This procedure is intended for the Lead Investigator and Protocol Development Team within the Clinical Trials Network as guidance for the consideration of multiple statistical comparisons within a protocol.  The Statistics Workgroup of the Data Management and Analysis Subcommittee will examine the proposed rationale for addressing multiple comparisons ...
openaire   +1 more source

Phenotypic variability in cystinosis: Lessons from an atypical case

Nefrología (English Edition)
Cystinosis is a rare monogenic autosomal recessive disorder caused by pathogenic variants in the CTNS gene, encoding cystinosin. Loss-of-function of cystinosin leads to intralysosomal cystine accumulation, resulting in cellular dysfunction and ...
Diego Toso, Monica Furlano, Adria Tinoco, Tania Sensat Saltor, Elisabet Ars, Roser Torra   +5 more
doaj   +1 more source

Integrated transcriptomic and tissue-validation analyses identify palmitoylation-associated biomarkers linked to sphingolipid metabolism and immune remodeling in psoriasis

Frontiers in Immunology
BackgroundPsoriasis is a chronic immune-mediated inflammatory skin disease characterized by epidermal dysfunction, aberrant keratinocyte activation, and complex immune remodeling. Although lipid dysregulation has increasingly been implicated in psoriasis,
Qingqiong Luo, Rongcan Shi, Rongcan Shi, Dandan Yang, Yijie Tang, Qinghui Xie, Yuling Shi, Yuling Shi, Fenyong Sun   +8 more
doaj   +1 more source

HKJEM abstracts (July & Aug 2026)

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 4, August 2026.
wiley   +1 more source

A zebrafish luminescent biosensor for kidney tubulopathy, metal toxicity and drug screening. [PDF]

Dis Model Mech
Lai H, Goldade M, Keller SA, Worms I, Luciani A, Neuhauss SCF, Slaveykova VI, Devuyst O, Chen Z.   +8 more
europepmc   +1 more source

Hematopoietic Stem-Cell Gene Therapy for Cystinosis. [PDF]

N Engl J Med
Barshop BA, Ball ED, Benador N, Trauner D, Phillips S, Dohil R, Afshari NA, Roy S, Campo Fernandes B, Kohn D, Shayan K, Everett JK, Bushman FD, Midgley J, Liang H, Sawyers A, Gangoiti JA, Panchal M, Ahmed I, Cherqui S.   +19 more
europepmc   +1 more source