Results 1 to 10 of about 57,597 (259)

Thymoquinone and 3HQ synergy inhibits CTX-M-15 ESBL [PDF]

Biomolecules & Biomedicine
Bacterial infections remain a significant cause of mortality worldwide, further aggravated by the escalating issue of antibiotic resistance. Extended-Spectrum Beta-Lactamases (ESBLs) pose a substantial challenge, capable of hydrolyzing various beta ...
Karem Ibrahem , Mohammad Alrabia, Asif Fatani, Sameer E.M. Alharthi, Hani Zakareya Asfour, Nabil A. Alhakamy, Hatoon A. Niyazi, Hisham N. Altayb, Ahmad M. Sait, Philip J.R. Day, Abdalbagi Alfadil   +10 more
doaj   +3 more sources

Detection of Clones B2-ST131-C2 and A-ST617 in Escherichia coli Producing Both CTX-M-15 and CTX-M-27 from Tunisian Community Patients [PDF]

Antibiotics, 2022
During a two-month period (2017–2018), 336 urine samples positive for Escherichia coli were collected from Tunisian patients. Of the 336 samples, 266 were collected from community patients and 70 from hospital settings.
Amel Mhaya, Rahma Trabelsi, Sabine Aillerie, Fatima M’Zali, Dominique Bégu, Slim Tounsi, Radhouane Gdoura, Corinne Arpin   +7 more
doaj   +2 more sources

Penicillanic Acid Sulfones Inactivate the Extended-Spectrum β-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: an Alternative Mechanism of β-Lactamase Inhibition [PDF]

mBio, 2022
β-Lactamases hydrolyze β-lactam antibiotics and are major determinants of antibiotic resistance in Gram-negative pathogens. Enmetazobactam (formerly AAI101) and tazobactam are penicillanic acid sulfone (PAS) β-lactamase inhibitors that differ by an ...
Philip Hinchliffe, Catherine L. Tooke, Christopher R. Bethel, Benlian Wang, Christopher Arthur, Kate J. Heesom, Stuart Shapiro, Daniela M. Schlatzer, Krisztina M. Papp-Wallace, Robert A. Bonomo, James Spencer   +10 more
doaj   +2 more sources

Faecal carriage of ESBL producing and colistin resistant Escherichia coli in avian species over a 2-year period (2017-2019) in Zimbabwe

Frontiers in Cellular and Infection Microbiology, 2022
IntroductionExtended spectrum beta-lactamase (ESBL) producing Escherichia coli have become widespread among food producing animals. These strains serve as a reservoir of antibiotic resistance genes (ARGs) and act as a possible source of infection to ...
Faustinos Tatenda Takawira, Faustinos Tatenda Takawira, Johann D. D. Pitout, Johann D. D. Pitout, Gaetan Thilliez, Tapfumanei Mashe, Tapfumanei Mashe, Ana Victoria Gutierrez, Robert A. Kingsley, Gisele Peirano, Jorge Matheu, Stanley Munyaradzi Midzi, Lusubilo Witson Mwamakamba, David L. Gally, Andrew Tarupiwa, Leckson Mukavhi, Marthie M. Ehlers, Marthie M. Ehlers, Sekesai Mtapuri-Zinyowera, Marleen M. Kock, Marleen M. Kock   +20 more
doaj   +1 more source

Prevalence of Multidrug-Resistant CTX-M Extended Spectrum Beta-Lactamase-Producing Escherichia coli From Different Bovine Faeces in China

Frontiers in Veterinary Science, 2022
CTX-M extended spectrum beta-lactamase-producing Escherichia coli cause severe health hazards in livestock breeding. To date, little is known about antibiotic resistance differences among bacterial isolates from yaks, cows, and beef cattle; therefore ...
Xiaojuan Wei, Xiaojuan Wei, Xiaojuan Wei, Weiwei Wang, Weiwei Wang, Weiwei Wang, Ningning Lu, Ningning Lu, Ningning Lu, Lingyu Wu, Lingyu Wu, Lingyu Wu, Zhen Dong, Zhen Dong, Zhen Dong, Bing Li, Bing Li, Bing Li, Xuzheng Zhou, Xuzheng Zhou, Xuzheng Zhou, Fusheng Cheng, Fusheng Cheng, Fusheng Cheng, Kairen Zhou, Kairen Zhou, Kairen Zhou, Haijian Cheng, Hongmei Shi, Jiyu Zhang, Jiyu Zhang, Jiyu Zhang   +31 more
doaj   +1 more source

Antimicrobial Resistance Genes and Diversity of Clones among Faecal ESBL-Producing Escherichia coli Isolated from Healthy and Sick Dogs Living in Portugal

Antibiotics, 2021
The purpose of this study was to analyse the prevalence and genetic characteristics of ESBL and acquired-AmpC (qAmpC)-producing Escherichia coli isolates from healthy and sick dogs in Portugal.
Isabel Carvalho, Rita Cunha, Carla Martins, Sandra Martínez-Álvarez, Nadia Safia Chenouf, Paulo Pimenta, Ana Raquel Pereira, Sónia Ramos, Madjid Sadi, Ângela Martins, Jorge Façanha, Fazle Rabbi, Rosa Capita, Carlos Alonso-Calleja, Maria de Lurdes Nunes Enes Dapkevicius, Gilberto Igrejas, Carmen Torres, Patrícia Poeta   +17 more
doaj   +1 more source

Escherichia ruysiae May Serve as a Reservoir of Antibiotic Resistance Genes across Multiple Settings and Regions

Microbiology Spectrum, 2023
Gut colonization with multidrug-resistant Enterobacterales (MDR-Ent) has reached worrisome levels worldwide. In this context, Escherichia ruysiae is a recently described species mostly found in animals.
Edgar I. Campos-Madueno, Claudia Aldeia, Parham Sendi, Andrea Endimiani   +3 more
doaj   +1 more source

Occurrence and Diversity of CTX-M-Producing Escherichia coli From the Seine River

Frontiers in Microbiology, 2020
CTX-M-producing Escherichia coli are spreading since 1999 both in clinical and in community settings. Environmental samples such as rivers have also been pointed out as being vectors for ESBL producers.
Delphine Girlich, Rémy A. Bonnin, Thierry Naas   +2 more
doaj   +1 more source

Co-existence of extended-spectrum β-lactamases bla CTX-M-9 and bla CTX-M-15 genes in Salmonella species isolated from febrile and diarrhoeagenic patients in Lagos, Nigeria: a cross-sectional study

European Journal of Medical Research, 2023
Background Resistance to different antimicrobial classes by Salmonella species has generated a global public health concern. The spread of extended-spectrum β-lactamases (ESBLs) bla CTX gene variants is also increasing.
Christopher O. Fakorede, Kehinde O. Amisu, Morteza Saki, Kabiru O. Akinyemi   +3 more
doaj   +1 more source

Epidemic plasmid carrying bla(CTX-M-15) in Klebsiella penumoniae in China. [PDF]

PLoS ONE, 2013
OBJECTIVE: To investigate the local epidemiology of Klebsiella penumoniae carrying bla(CTX-M-15) in southern China and to characterize the genetic environment of bla(CTX-M-15).
Chao Zhuo, Xiao-qiang Li, Zhi-yong Zong, Nan-Shan Zhong   +3 more
doaj   +1 more source