Results 21 to 30 of about 57,597 (259)

Comparative Genetic Characterization of CTX-M-Producing Escherichia coli Isolated from Humans and Pigs with Diarrhea in Korea Using Next-Generation Sequencing

Microorganisms, 2023
Pathogenic E. coli causes intra- and extraintestinal diseases in humans and pigs and third-generation cephalosporins are the primary option for the treatment of these diseases.
Kwang-Won Seo, Kyung-Hyo Do, Wan-Kyu Lee
doaj   +1 more source

Characterization of extended-spectrum β-lactamases produced by Escherichia coli isolated from hospitalized and nonhospitalized patients : emergence of CTX-M-15-producing strains causing urinary tract infections [PDF]

, 2010
Extended-spectrum β-lactamase-producing Escherichia coli isolates were obtained from hospitalised and non-hospitalised patients in Belgium between August 2006 and November 2007.
Butaye, Patrick, Claeys, Geert, Dewulf, Jeroen, Haesebrouck, Freddy, Herman, Lieve, Heyndrickx, Marc, Lontie, Marc, Martel, An, Persoons, Davy, Smet, Annemieke, Van Meensel, Britt   +10 more
core   +1 more source

First Description of CTX-M-15-Producing Klebsiella pneumoniae in Portugal [PDF]

Antimicrobial Agents and Chemotherapy, 2005
The first CTX-M-15 β-lactamase was found in several enterobacterial isolates from India in 1999 (4). Worldwide spread of CTX-M-15 β-lactamases is now well documented (1-5, 7, 8, 12). CTX-M β-lactamases confer high-level resistance to cefotaxime, ceftriaxone, and aztreonam and are well inhibited by clavulanate and tazobactam (10, 11).
Conceicao, T, Brizio, A, Duarte, A, Lito, LM, Cristino, JM, Salgado, MJ   +5 more
openaire   +3 more sources

Molecular epidemiology of CTX-M-producing escherichia coli isolates at a tertiary medical center in western pennsylvania [PDF]

, 2009
A combination of phenotypic and genotypic methods was used to investigate 70 unique Escherichia coli clinical isolates identified as producing extended-spectrum beta-lactamases (ESBLs) at a medical center in Pittsburgh, PA, between 2007 and 2008.
Adams-Haduch, Jennifer M., Doi, Yohei, Ewan, Lindsay, Muto, Carlene A., Pasculle, Anthony W., Paterson, David L., Sidjabat, Hanna E., Tian, Guo-Bao   +7 more
core   +1 more source

Collateral sensitivity constrains resistance evolution of the CTX-M-15 β-lactamase [PDF]

Nature Communications, 2019
Abstract Antibiotic resistance is a major challenge to global public health. Discovery of new antibiotics is slow and to ensure proper treatment of bacterial infections new strategies are needed. One way to curb the development of antibiotic resistance is to design drug combinations where the development of resistance against one drug
Carola E. H. Rosenkilde, Christian Munck, Andreas Porse, Marius Linkevicius, Dan I. Andersson, Morten O. A. Sommer   +5 more
openaire   +5 more sources

Portable Differential Detection of CTX-M ESBL Gene Variants, blaCTX-M-1 and blaCTX-M-15, from Escherichia coli Isolates and Animal Fecal Samples Using Loop-Primer Endonuclease Cleavage Loop-Mediated Isothermal Amplification

Microbiology Spectrum, 2023
Cefotaximase-Munich (CTX-M) extended-spectrum beta-lactamase (ESBL) enzymes produced by Enterobacteriaceae confer resistance to clinically relevant third-generation cephalosporins.
Owen Higgins, Alexandra Chueiri, Louise O'Connor, Sinéad Lahiff, Liam Burke, Dearbhaile Morris, Nicola Maria Pfeifer, Belén González Santamarina, Christian Berens, Christian Menge, Manuela Caniça, Vera Manageiro, Veljo Kisand, Marwa M. Hassan, Brian Gardner, Arnoud H. M. van Vliet, Roberto M. La Ragione, Bruno Gonzalez-Zorn, Terry J. Smith   +18 more
doaj   +1 more source

Massive Increase, Spread, and Exchange of Extended Spectrum {beta}-Lactamase-Encoding Genes Among Intestinal Enterobacteriaceae in Hospitalized Children With Severe Acute Malnutrition in Niger. [PDF]

, 2011
Background. From the time of CTX-M emergence, extended-spectrum β-lactamase-producing enterobacteria (ESBL-E) have spread worldwide in community settings as well as in hospitals, particularly in developing countries.
Andremont, A, Angebault, C, Armand-Lefèvre, L, Barbier, F, de Rekeneire, N, El Mniai, A, Hugede, H-C, Jacquier, H, Janssens, A-C, Page, A-L, Raskine, L, Ruppé, E, Sayadi, S, Woerther, P-L   +13 more
core   +2 more sources

Phenotypic microarrays suggest Escherichia coli ST131 is not a metabolically distinct lineage of extra-intestinal pathogenic E. coli [PDF]

, 2014
Extraintestinal pathogenic E. coli (ExPEC) are the major aetiological agent of urinary tract infections (UTIs) in humans. The emergence of the CTX-M producing clone E. coli ST131 represents a major challenge to public health worldwide.
A Coelho, A Cove-Smith, A McNally, A McNally, Abdulaziz Alqasim, Alan McNally, AR Pacheco, AT Anfora, B Foxman, B Foxman, BR Bochner, C Le Bouguénec, DM Livermore, F Alhashash, G Clark, G Croxall, G Croxall, G Peirano, Gemma Clark, Jane Newcombe, JDD Pitout, JL Smith, JR Johnson, JR Johnson, L Rohmer, L Zhang, LM Durso, M Akram, MH Nicolas-Chanoine, MS Litwin, N Woodford, Niyaz Ahmed, O Clermont, OR Homann, R Welch, Richard Emes, Roberto La Ragione, S Farajnia, SH Lau, SH Lau, SK Sheppard, SL Chen, TJ Carver, TM Gibreel, TM Gibreel, V Leflon-Guibout, V Pancholi   +46 more
core   +9 more sources

ESBL-Producing Salmonella enterica Serovar Typhi in Traveler Returning from Guatemala to Spain

Emerging Infectious Diseases, 2014
We report a case of typhoid fever in a traveler returning to Spain from Guatemala that was caused by Salmonella enterica serovar Typhi which produced an extended-spectrum β-lactamase (ESBL).
Anna Fàbrega, Nuria Piedra-Carrasco, Fernando Salvador, Virginia Rodríguez, Adrián Sánchez-Montalvá, Anna M. Planes, Israel Molina, M. Nieves Larrosa   +7 more
doaj   +1 more source

Molecular epidemiology and characterization of an outbreak causing Klebsiella pneumoniae clone carrying chromosomally located bla CTX-M-15 at a German University-Hospital [PDF]

, 2015
Background: Multi-drug resistant Klebsiella pneumoniae strains are a common cause of health care associated infections worldwide. Clonal spread of Klebsiella pneumoniae isolates carrying plasmid mediated CTX-M-15 have been commonly reported. Limited data
Chakraborty, Trinad, Domann, Eugen, Falgenhauer, Linda, Fritzenwanker, Moritz, Hain, Torsten, Imirzalioglu, Can, Mshana, Stephen E.   +6 more
core   +2 more sources