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Alterations in gut microbiota and metabolomic profiles in acute stroke: insights into brain-gut axis dysregulation. [PDF]
Front MicrobiolChen J, Wu X, Wang X, Yuan R, Zhu Q.
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Food and Chemical Toxicology, 2014
Cucurbitacin B, a member of the cucurbitaceae family, can act as a STAT3 signaling inhibitor to regulate the growth of hepatocellular carcinoma. STAT3 signaling has been shown to inhibit adipocyte differentiation through C/EBPα and PPARγ. Based on these studies, we hypothesized that cucurbitacin B would prevent PPARγ mediated adipocyte differentiation ...
Dong Kwon Yang +2 more
exaly +3 more sources
Cucurbitacin B, a member of the cucurbitaceae family, can act as a STAT3 signaling inhibitor to regulate the growth of hepatocellular carcinoma. STAT3 signaling has been shown to inhibit adipocyte differentiation through C/EBPα and PPARγ. Based on these studies, we hypothesized that cucurbitacin B would prevent PPARγ mediated adipocyte differentiation ...
Dong Kwon Yang +2 more
exaly +3 more sources
Cucurbitacin glycosides from Citrullus colocynthis
Phytochemistry, 1989Abstract The chloroform extract of Citrullus colocynthis yielded four cucurbitacin glycosides which were identified spectroscopically as 2- O -β- d -glucopyranosyl-cucurbitacin I, 2- O -β- d -glucopyranosyl-cucurbitacin E, 2- O -β- d -glucopyranosyl-cucurbitacin L and the novel glycoside, 2- O -β- d -glucopyranosyl-(22–27)-hexanorcucurbitacin I ...
Natiq A.R. Hatam +2 more
exaly +2 more sources
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2017
Cucurbitacin B (CuB) and cucurbitacin E (CuE) are tetracyclic triterpene compounds from Cucurbitaceae, and the main bioactive compounds of cucurbitacins tablets that used to treatment of chronic hepatitis. Pharmacological research has been very comprehensive, and there are few studies on pharmacokinetics, especially about CuE. An Ultra High Performance
Wenbo Zhu, Chun-Juan Yang, Gaosong Wu
exaly +3 more sources
Cucurbitacin B (CuB) and cucurbitacin E (CuE) are tetracyclic triterpene compounds from Cucurbitaceae, and the main bioactive compounds of cucurbitacins tablets that used to treatment of chronic hepatitis. Pharmacological research has been very comprehensive, and there are few studies on pharmacokinetics, especially about CuE. An Ultra High Performance
Wenbo Zhu, Chun-Juan Yang, Gaosong Wu
exaly +3 more sources
Phytomedicine, 2023
BACKGROUND The mortality rate of liver cancer ranks third in the world, and hepatocellular carcinoma (HCC) is a malignant tumor of the digestive tract.
Qizhang Li +5 more
semanticscholar +1 more source
BACKGROUND The mortality rate of liver cancer ranks third in the world, and hepatocellular carcinoma (HCC) is a malignant tumor of the digestive tract.
Qizhang Li +5 more
semanticscholar +1 more source
Cucurbitacins: Nature’s Wonder Molecules
Current Traditional Medicine, 2022Abstract: Over the past decades, several natural constituents belonging to different classes have been isolated from plants for medicinal purposes. Cucurbitacins is one such type of natural compound. Cucurbitacin is a class of biochemical compounds that some plants, notably members of the pumpkin and gourd family, Cucurbitaceae produce and function as
Sonal H. Kanani, Devang J. Pandya
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Journal of Ethnopharmacology, 2023
ETHNOPHARMACOLOGICAL RELEVANCE Cholestatic liver injury (CLI) is a pathologic process with the impairment of liver and bile secretion and excretion, resulting in an excessive accumulation of bile acids within the liver, which leads to damage to both bile
Shuang-Hua Dai +10 more
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ETHNOPHARMACOLOGICAL RELEVANCE Cholestatic liver injury (CLI) is a pathologic process with the impairment of liver and bile secretion and excretion, resulting in an excessive accumulation of bile acids within the liver, which leads to damage to both bile
Shuang-Hua Dai +10 more
semanticscholar +1 more source
Phytomedicine, 2023
BACKGROUND Ovarian cancer is a serious threat to women's health, and resistance to chemotherapeutic drugs constitutes one of the principal reasons for ovarian cancer recurrence and the low overall survival rate.
Shuanghong Yin +4 more
semanticscholar +1 more source
BACKGROUND Ovarian cancer is a serious threat to women's health, and resistance to chemotherapeutic drugs constitutes one of the principal reasons for ovarian cancer recurrence and the low overall survival rate.
Shuanghong Yin +4 more
semanticscholar +1 more source
New Phytologist, 2023
Membrane-localized transporters constitute important components for specialized metabolism in plants. However, due to the vast array of specialized metabolites produced by plants, and the large families of transporter genes, knowledge about the intra ...
Yongshuo Ma +8 more
semanticscholar +1 more source
Membrane-localized transporters constitute important components for specialized metabolism in plants. However, due to the vast array of specialized metabolites produced by plants, and the large families of transporter genes, knowledge about the intra ...
Yongshuo Ma +8 more
semanticscholar +1 more source