Results 211 to 220 of about 20,694 (254)

Cucurbitacins from Bryonia cretica

Phytochemistry Letters, 2010
From the roots of Bryonia cretica L. two new cucurbitacins, isocucurbitacins G (1) and H (2), along with three known cucrbitacins, cucurbitacins G (3), H (4), and J (5) were isolated. The structures of 1 and 2 were determined on the basis of 1D and 2D NMR spectroscopic analysis and X-ray crystallography.
Amal A. Sallam, Yukio Hitotsuyanagi, El-Sayed S. Mansour, Atallah F. Ahmed, Sahar Gedara, Haruhiko Fukaya, Koichi Takeya   +6 more
openaire   +1 more source

Cucurbitacins from Wilbrandia ebracteata

Phytochemistry, 1992
Abstract Three new cucurbitacins were isolated from the roots of Wilbrandia ebracteata and their structures established as 16α, 23α-epoxy-2β,3β,20β-trihydroxy-10α,23β-cucurbit-5,24-dien-11-one, 16α,23α-epoxy-2β,3β,20β-trihydroxy- 10α,23α-cucurbit-5,24-dien-11-one and 2β,3β,16α,20,25-pentahydroxy-10α-cucurbit-5,23-dien-11-one, mainly by spectroscopy.
Eloir Paulo Schenkel, Mareni Rocha Farias, Ralf Mayer, Eberhard Breitmaier, Gerhard Rücker   +4 more
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Cucurbitacin I exerts its anticancer effects by inducing cell cycle arrest via the KAT2a-ube2C/E2F1 pathway and inhibiting HepG2-induced macrophage M2 polarization.

Biochemical and Biophysical Research Communications - BBRC
Hepatocellular carcinoma (HCC) is one of the most common malignancies globally, particularly prevalent in China, where it accounts for nearly half of the world's new cases and deaths each year, but has limited therapeutic options.
Xiaocheng Gong, Yunfei Liu, Keying Liang, Zixi Chen, Ke Ding, Li Qiu, Jinfen Wei, Hongli Du   +7 more
semanticscholar   +1 more source

Synergistic effect of cucurbitacin E and myricetin on Anti-Non-Small cell lung cancer: Molecular mechanism and therapeutic potential.

Phytomedicine, 2022
BACKGROUND Non-small cell lung cancer (NSCLC) is associated with extremely high morbidity and mortality rates worldwide. Citrullus colocynthis (L.) Schrad, widely distributed in Asian and African countries, is used to treat cancers in traditional Uyghur ...
Jinfang Zhang, Baht Aray, Yan Zhang, Yinglu Bai, Tao Yuan, Shilan Ding, Y. Xue, Xiulan Huang, Zhiyong Li   +8 more
semanticscholar   +1 more source

Cucurbitacins from Picrorhiza kurrooa

Phytochemistry, 1991
Abstract Seven new cucurbitacins were isolated from the roots of Picrorhiza kurrooa . On the basis of UV, 1 H, 13 C NMR, 2D 1 H, 1 H- 13 C NMR and mass spectroscopy their structures were determined as 25-(acetyloxy)-2-(β- d -glucopyranosyloxy)-3,16-dihydroxy-9-methyl-19-norlanosta-5,23-dien-22-one, 25-(acetyloxy)-2-(β- d -glucopyranosyloxy)-3,16 ...
Hermann Stuppner, Ernst P. Müller, Hildebert Wagner   +2 more
openaire   +1 more source

Cucurbitacin glycosides from Cabeça-de-negro

Phytochemistry, 1995
Five cucurbitacin glycosides named cabenosides D-L were isolated from 'Cabeça-de-negro', the roots of Caput nigri. Among them, the structures of cabenosides D-H were elucidated as 10 alpha-cucurbit-5-en-11-oxo-3 beta,24R,25-triol-3-O-beta-D-glucopyranoside, 10 alpha-cucurbit-5-en-24-oxo-3 beta, 11 alpha,25-triol-25-O-beta-D- glucopyranosyl, [3,O-beta-D-
K, Nakano, Y, Kanai, K, Murakami, Y, Takaishi   +3 more
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Cucurbitacin glucosides fromCitrullus colocynthis

Natural Product Research, 2006
A new cucurbitacin glucoside 2-O-beta-D-glucopyranosyl-16alpha-20R-dihydroxy-cucurbita-1,5,23E,25(26)-tetraen-3,11,22-trione (1) has been isolated from the methanolic extract of the fruits of Citrulluscolocynthis. The structure has been assigned on the basis of spectral analysis including 1D and 2D NMR techniques.
Durey, Nayab, Dildar, Ali, Nuzhat, Arshad, Abdul, Malik, M Iqbal, Choudhary, Zaheer, Ahmed   +5 more
openaire   +2 more sources

Nor-cucurbitacin glucosides from Caputo nigri

Phytochemistry, 1994
Three new nor-cucurbitacin glucosides were isolated from the root of Caputo nigri (Cabeça-de-negro) and their structures established as 29-nor-1,2,3,4,5,10-dehydro-2,3,16 alpha,20R, 22 zeta,25-hexahydroxy-11-oxocucurbita-6,23-diene 2-O-beta-D-glucopyranoside and 2-O-beta-D-glucopyranosyl(1-2)beta-D- glucopyranoside(sophorose), and 1,2,3,4,5,10-dehydro ...
K, Nakano, Y, Kanai, K, Murakami, Y, Takaishi, T, Tomimatsu   +4 more
openaire   +2 more sources

13C NMR spectroscopy of cucurbitacins

Tetrahedron, 1983
Abstract The 13 C NMR spectra of nine representative cucurbitacins have been analysed for signal assignment, by deduction and selective comparison. Detailed 1 H NMR data have been provided.
Vincent Vande Velde, David Lavie
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Cucurbitacine als stathmokinetische Wirkstoffe

Planta, 1971
A synergism of colchicine and different cucurbitacins has been shown, to be a cause in the formation of ball-metaphases in Bryonia species. The bitter principles cucurbitacin L and I, dihydrocucurbitacin B, and tetrahydrocucurbitacin I, which were examined more closely with respect to their karyological effects, were shown to give rise to C-metaphases ...
openaire   +1 more source