Results 41 to 50 of about 15,560 (192)

Direct interaction of Cucurbitacin E isolated from Alsomitra macrocarpa to actin filament [PDF]

Cytotechnology, 2007
A methanol extract of Alsomitra macrocarpa leaves and branches induced a marked alteration of cell morphology in a human stellate cell line (LX-2). Similar morphologic alterations were observed in several other cell lines. Active compound was purified from the extract and determined to be cucurbitacin E (Cuc E).
Keiko, Momma, Yuko, Masuzawa, Naomi, Nakai, Moeko, Chujo, Akira, Murakami, Noriyuki, Kioka, Yasunori, Kiyama, Toru, Akita, Masaya, Nagao   +8 more
openaire   +2 more sources

Derivatives of Cucurbitacin-E-glucoside produced by Curvularia lunata NRRL 2178: Anti-inflammatory, antipyretic, antitumor activities, and effect on biochemical parameters

Future Journal of Pharmaceutical Sciences, 2017
Cucurbitacin E glucoside (1) is a tetracyclic triterpenoid glucoside, isolated from Cucurbitaceae plants. In the present study the pharmacological and biochemical effects of cucurbitacin-E-glucoside and two of its microbial transformation derivatives (2 ...
Abdelfattah A. Abdelkhalek, Abdel-Monem M.A. Sharaf, Mohamed Rabie, Hussein I. El-Subbagh   +3 more
doaj   +1 more source

Isca amilácea de cucurbitacina (Lagenaria vulgaris L.) promove maior eficiência do inseticida carbaril no controle de Diabrotica speciosa, em laboratório Cucurbitacin (Lagenaria vulgaris L.) starch bait improves efficiency of carbaril insecticide in the Diabrotica speciosa, in laboratory

Ciência Rural, 2008
Diabrotica speciosa (Germar, 1824) (Coleoptera: Chrysomelidae: Galerucinae) é uma importante praga polífaga na América Latina. Seu controle é realizado com inseticidas sintéticos, o que causa problemas ambientais.
Adriana Yatie Mikami, Maurício Ursi Ventura   +1 more
doaj   +1 more source

Migrastatics—anti-Metastatic and Anti-invasion Drugs:Promises and Challenges [PDF]

, 2017
In solid cancers, invasion and metastasis account for more than 90% of mortality. However, in the current armory of anticancer therapies, a specific category of anti-invasion and antimetastatic drugs is missing.
Gandalovičová, Aneta, Rosel, Daniel, Fernandes, Michael, Veselý, Pavel, Heneberg, Petr, Čermák, Vladimír, Petruželka, Luboš, Kumar, Sunil, Sanz-Moreno, Victoria, Brábek, Jan   +9 more
core   +1 more source

Inhibitory Activity of Leaves Extracts of Citrullus colocynthis Schrad. on HT29 Human Colon Cancer Cells [PDF]

, 2016
Aims: Citrullus colocynthis is a plant endemic in Asia, Africa and in the Mediterranean basin. It is used in folk medicine against infections, inflammations and cardiovascular and immune-related diseases.
Aouni, M, Arru, Laura, Bekkouche, K, Buschini, A., Galati, S, Jamali, Ca, Marzouk, B, Marzouk, Z, Mussi, F   +8 more
core   +1 more source

Quantification of cucurbitacins B and E in Coccinia grandis fruit ethanolic extract and their anti-inflammatory effects in SARS-CoV-2 protein-stimulated macrophages

Cogent Food & Agriculture
Food-derived bioactive compounds are increasingly being recognized for their potential in modulating inflammatory responses associated with post-infectious health conditions.
Rattanathorn Choonong, Laddawan Senggunprai, Waraporn Putalun, Waranyoo Phoolcharoen   +3 more
doaj   +1 more source

Cytotoxic Effect of Freeze-Dried Extract of Ecballium elaterium Fruit on Gastric Adenocarcinoma (AGS) and Esophageal Squamous Cell Carcinoma (KYSE30) Cell Lines [PDF]

Purpose Ecballium elaterium (L.) A. Rich (Cucurbitaceae), also known as the “squirting cucumber,” is a wild medicinal plant found abundantly in Moghan, Ardabil province, Iran.
بهلولی, شهاب, جاهد, شهرام, جعفری, ناصر   +2 more
core   +1 more source

Bitter Melon (Momordica charantia) Extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in Ovarian Cancer Cells Through Targeting AMPK Signaling Cascade [PDF]

, 2016
OBJECTIVE: Acquired chemoresistance is a major obstacle in the clinical management of ovarian cancer. Therefore, searching for alternative therapeutic modalities is urgently needed.
Al Rawahi T, D. Grahame Hardie, David W. Chan, Ferla R, Fiona A. Ross, Hextan Y. S. Ngan, Jinbiao Zhan, Kikkawa F, Limtrakul P, Mingo M. H. Yung, Pinto AL, Teh MT, Thomas H. Y. Leung   +12 more
core   +3 more sources

A Systematic Review of Iran’s Medicinal Plants With Anticancer Effects [PDF]

, 2015
Increase in cases of various cancers has encouraged the researchers to discover novel, more effective drugs from plant sources. This study is a review of medicinal plants in Iran with already investigated anticancer effects on various cell lines.
Asadi-Samani, Majid., Aslani, Elahe., Kooti, Wesam., shirzad, Hedayatollah.   +3 more
core   +1 more source

Vaccarin Improves Myocardial Ischemia–Reperfusion Injury by Attenuating Oxidative Stress and Ferroptosis Through Reducing NOX4‐Modulated JAK2/STAT3 Pathway Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Vaccarin is a naturally occurring flavonoid glycoside with cardioprotective properties; however, its involvement in myocardial ischemia–reperfusion (MI/R) injury remains poorly defined. We herein investigated whether vaccarin protects cardiomyocytes from MI/R‐induced dysfunction in vivo and in vitro and examined the associated molecular ...
Han Yang, Mi Zhou, Feng‐Cai Zhang
wiley   +1 more source