Results 51 to 60 of about 2,372 (212)
Cucurbitacin E has neuroprotective properties and autophagic modulating activities on dopaminergic neurons [PDF]
, 2014 Natural molecules are under intensive study for their potential as preventive and/or adjuvant therapies for neurodegenerative disorders such as Parkinson’s disease (PD).
Arel-Dubeau, Anne-Marie +8 more
core +4 more sources
Cucurbitacins as kairomones for diabroticite beetles [PDF]
Proceedings of the National Academy of Sciences, 1980 The characteristic bitter substances of the Cucurbitaceae act as kairomones for a large group of diabroticite beetles (Chrysomelidae, Galerucinae, Luperini), promoting host selection and compulsive feeding behavior. These beetles (e.g., Diabrotica undecimpunctata howardi ) respond to as little as 1 ng of ...
R L, Metcalf, R A, Metcalf, A M, Rhodes
openaire +2 more sources
Pentacyclic and hexacyclic cucurbitacins from Elaeocarpus petiolatus
Phytochemistry, 2022 Four undescribed cucurbitacins, designated as petiolaticins A-D, and four known cucurbitacins were isolated from the bark and leaves of Elaeocarpus petiolatus (Jack) Wall. Their chemical structures were elucidated based on detailed analyses of the NMR and MS data.
Eun-Seon Cho +8 more
openaire +2 more sources
Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs [PDF]
, 2018 Rocaglamide has been reported to sensitize several cell types to TRAIL-induced apoptosis. In recent years, advances in synthetic techniques have led to generation of novel rocaglamide analogs.
Brown, Lauren E. +5 more
core +2 more sources
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Vaccarin is a naturally occurring flavonoid glycoside with cardioprotective properties; however, its involvement in myocardial ischemia–reperfusion (MI/R) injury remains poorly defined. We herein investigated whether vaccarin protects cardiomyocytes from MI/R‐induced dysfunction in vivo and in vitro and examined the associated molecular ...
Han Yang, Mi Zhou, Feng‐Cai Zhang
wiley +1 more source
Relevamiento de la producción de lacasa en aislamientos de Colletotrichum (Ascomycota), agente causal de antracnosis de la Soja [PDF]
, 2007 Colletotrichum truncatum es el hongo patógeno más comúnmente asociado con la antracnosis de soja. Aunque la enzima ligninolítica lacasa se relaciona con la patogenicidad de un amplio rango de hongos fitopatógenos, su rol biológico en la interacción ...
Gally, Marcela Edith +3 more
core
Food prospects and nutraceutical attributes of Momordica species: A potential tropical bioresources – A review [PDF]
, 1937 Plants with potential therapeutic values have been used from time immemorial to cure various ailments and infectious diseases. Of late, scientific evidences have been provided on the potential therapeutic agent exhibited by certain traditionally used ...
Nagarani, Gunasekaran +2 more
core +1 more source
Phytotherapy Research, EarlyView.Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou +9 more
wiley +1 more source
The cytotoxic Activity of Cucurbitacin E and Busulphan on ovarian and stomach cancer cells in vitro : a comparative study [PDF]
, 1996 A comparative study of the cytotoxicity of cucurbitacin E, a natural product, and busulphan on human ovarian and stomach cell lines was carried out.
Attard, Everaldo +3 more
core
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
Plant, Cell &Environment, EarlyView.ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source