Results 61 to 70 of about 2,372 (212)
Cucurbitacin E inhibits the Yes‑associated protein signaling pathway and suppresses brain metastasis of human non‑small cell lung cancer in a murine model. [PDF]
, 2019 Human non‑small cell lung cancer (NSCLC) is associated with an extremely poor prognosis especially for the 40% of patients who develop brain metastasis, and few treatment strategies exist.
Hsu, Ping-Chih +9 more
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Health Science Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background and Aim Janus kinases/signal transducers and activators of transcription (JAK/STAT) pathway is crucial for various stages of immunity, from innate to adaptive responses. Type 1 IFNs activate JAK/STAT pathway by binding to receptors on JAK, phosphorylating STAT and upregulating interferon‐stimulated genes (ISGs) leading to cytokines ...
Esimebia Adjovi Amegashie +7 more
wiley +1 more source
Antioxidants, 2022 Coccinia grandis contains secondary metabolites, such as flavonoids, phenolic acids, terpenoids, alkaloids, sterols, and glycosides, which are known to have in vitro antioxidant, antidiabetic, anti-inflammatory, and antidyslipidemic activities.
In Young Lee, Nami Joo
doaj +1 more source
Advanced Science, Volume 13, Issue 24, 27 April 2026.Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu +10 more
wiley +1 more source
BMC Complementary and Alternative Medicine, 2018 Background Cucumis prophetarum var. prophetarum is used in Saudi folk medicine for treating liver disorders and grows widely between Abha and Khamis Mushait City, Saudi Arabia.
Abdulrhman Alsayari +5 more
doaj +1 more source
, 2006 Poisoning due to Cucurbitaceous vegetables seems to be linked to intake of immensely bitter vegetables. The bitter and toxic compounds in these vegetables are cucurbitacins, which are well known in wild varieties of these food plants and their related species. The cultivated forms, on the other hand, have during cultivation been selected for being free
Gry, Jørn +2 more
openaire +3 more sources
Cucurbitacins: elucidation of their interactions with the cytoskeleton [PDF]
PeerJ, 2017 Cucurbitacins, a class of toxic tetracyclic triterpenoids in Cucurbitaceae, modulate many molecular targets. Here we investigated the interactions of cucurbitacin B, E and I with cytoskeletal proteins such as microtubule and actin filaments.
Xiaojuan Wang +3 more
doaj +2 more sources
Study on seasonal variation on the content of Cucurbitacin of various vegetative parts of Trichosanthes cucumerina L. var. cucumerina [PDF]
, 2011 The total cucurbitacin content produced in the different parts of T. cucumerina L. var. cucumerina viz., fruit, stem and leaves with time and temperature was studied during the year 2007-08.
Attard, Everaldo +3 more
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Pengaruh Pemberian Ekstrak Pare(Momordica Charantia,L)Terhadap Struktur Histologi Testis dan Epididimis Tikus Jantan (Rattus Norvegicus) Spraque Dawley® [PDF]
, 2014 Senyawa aktif yang terdapat dalam pare yaitu kukurbitasin yang termasuk golongan glikosida tripenoid diduga bekerja menghambat perkembangan sel spermatogenik melalui efek sitotosik dan melalui efek hormonal.Tujuan Penelitian untuk mengukur dan ...
Arsyad, A. (Arsyad) +2 more
core +2 more sources
MedComm, Volume 7, Issue 4, April 2026.This study identified 10 potential causality between metabolites and blood pressure and found potential genetic regulators of two metabolites. Multiomics integration revealed that a genetic variant near the omega‐3 metabolism genes (FADS1/FADS2) may influence blood pressure regulation by modulating prostaglandin E3 levels.
Yuanjiao Liu +5 more
wiley +1 more source