Results 61 to 70 of about 2,327 (197)

The cytotoxic Activity of Cucurbitacin E and Busulphan on ovarian and stomach cancer cells in vitro : a comparative study [PDF]

open access: yes, 1996
A comparative study of the cytotoxicity of cucurbitacin E, a natural product, and busulphan on human ovarian and stomach cell lines was carried out.
Attard, Everaldo   +3 more
core  

Glucosinolate hydrolysis products suppress entomopathogenic nematodes in vitro but do not protect sequestering flea beetle larvae in vivo

open access: yesPest Management Science, Volume 82, Issue 4, Page 3603-3612, April 2026.
The flea beetle's glucosinolate‐based chemical defense fails to protect larvae from nematode infection. However, the defense inhibits the nematode's symbiotic bacteria, thereby potentially impairing nematode reproduction and biocontrol success. Abstract BACKGROUND The efficacy of entomopathogenic nematodes (EPNs) in the biological control of insect ...
Johannes Körnig   +9 more
wiley   +1 more source

Isolation of anticancer constituents from Cucumis prophetarum var. prophetarum through bioassay-guided fractionation

open access: yesBMC Complementary and Alternative Medicine, 2018
Background Cucumis prophetarum var. prophetarum is used in Saudi folk medicine for treating liver disorders and grows widely between Abha and Khamis Mushait City, Saudi Arabia.
Abdulrhman Alsayari   +5 more
doaj   +1 more source

Phytochemical Analysis of Veratrum Alkaloids in Medicinal Veratrum Globules Using High‐Performance Liquid Chromatography Coupled With Tandem Mass Spectrometry

open access: yesBiomedical Chromatography, Volume 40, Issue 3, March 2026.
ABSTRACT Veratrum L. species have been used in traditional medicine for centuries due to their bioactive properties, yet they also contain toxic steroid alkaloids that pose potential health risks when present in herbal preparations. Reliable analytical approaches are therefore essential to ensure product safety, protect consumer health and assess ...
Julia Siegle, Jörg Pietsch
wiley   +1 more source

Pengaruh Pemberian Ekstrak Pare(Momordica Charantia,L)Terhadap Struktur Histologi Testis dan Epididimis Tikus Jantan (Rattus Norvegicus) Spraque Dawley® [PDF]

open access: yes, 2014
Senyawa aktif yang terdapat dalam pare yaitu kukurbitasin yang termasuk golongan glikosida tripenoid diduga bekerja menghambat perkembangan sel spermatogenik melalui efek sitotosik dan melalui efek hormonal.Tujuan Penelitian untuk mengukur dan ...
Arsyad, A. (Arsyad)   +2 more
core   +2 more sources

The plant-derived triterpenoid, cucurbitacin B, but not cucurbitacin E, inhibits the developmental transition associated with ecdysone biosynthesis in Drosophila melanogaster [PDF]

open access: yes, 2021
In insects, some sterols are essential not only for cell membrane homeostasis, but for biosynthesis of the steroid hormone ecdysone. Dietary sterols are required for insect development because insects cannot synthesize sterols de novo.
Fujikawa, Yuuta   +8 more
core   +1 more source

Cucurbitacins in plant food

open access: yes, 2006
Poisoning due to Cucurbitaceous vegetables seems to be linked to intake of immensely bitter vegetables. The bitter and toxic compounds in these vegetables are cucurbitacins, which are well known in wild varieties of these food plants and their related species. The cultivated forms, on the other hand, have during cultivation been selected for being free
Gry, Jørn   +2 more
openaire   +3 more sources

Molecular Mechanism of Mulberrin Regulating Lipid Metabolism Homeostasis Based on the Gut–Liver Axis Fiaf/AMPK Signaling Pathway

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
The molecular mechanism for mulberrin regulating lipid metabolism homeostasis. ABSTRACT Lipid metabolism disorders and the induced metabolic diseases have risen to become one of the primary public health issues. Our preliminary experimental results confirmed that mulberry leaf flavonoid extract exhibited efficacy in lipid metabolism regulation; the ...
Qian Li   +6 more
wiley   +1 more source

Cucurbitacins: elucidation of their interactions with the cytoskeleton [PDF]

open access: yesPeerJ, 2017
Cucurbitacins, a class of toxic tetracyclic triterpenoids in Cucurbitaceae, modulate many molecular targets. Here we investigated the interactions of cucurbitacin B, E and I with cytoskeletal proteins such as microtubule and actin filaments.
Xiaojuan Wang   +3 more
doaj   +2 more sources

Identification and Quantification of Key Phytochemicals, Phytohormones, and Antioxidant Properties in Coccinia grandis during Fruit Ripening

open access: yesAntioxidants, 2022
Coccinia grandis contains secondary metabolites, such as flavonoids, phenolic acids, terpenoids, alkaloids, sterols, and glycosides, which are known to have in vitro antioxidant, antidiabetic, anti-inflammatory, and antidyslipidemic activities.
In Young Lee, Nami Joo
doaj   +1 more source

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