Results 41 to 50 of about 1,425,464 (309)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Seasonal variation in supply and prices of strawberry in Minas Gerais’ CEASA, BRAZIL

Ciência Rural, 2021
: The research studied the seasonal variation in supply and prices of strawberry practiced in the state of Minas Gerais, represented by the units of the CEASAMINAS, as well as components of this supply for each major supply region in the state, in the ...
Wesley Augusto Florêncio Jordão, Luis Felipe Lima e Silva   +1 more
doaj   +1 more source

The impact of shifting cultivation in the forestry ecosystems of timor-leste [PDF]

, 2012
Every year thousands of hectares of forest are destructed as a result of the practice of swidden agriculture, shifting cultivation or "slush and burn" causing changes in forest ecosystems.
Henriques, Pedro, Laranjeira, Pedro, Maria, Jesus, Narciso, Vanda   +3 more
core  

Studies in Soil Cultivation.: V. Rotary Cultivation

The Journal of Agricultural Science, 1930
Experiments extending over the four years, 1926–9 inclusive, have been carried out on a heavy and stony loam soil to compare rotary cultivation with normal methods for the production of a seed-bed. The work has been confined to spring-sown crops—swedes and barley—and to spring cultivations.Rotary cultivation gives earlier and better germination of seed,
Keen, B. A., Staff of the Soil Physics Department   +1 more
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Enriched iron(III)-reducing bacterial communities are shaped by carbon substrate and iron oxide mineralogy

Frontiers in Microbiology, 2012
Iron (Fe) oxides exist in a spectrum of structures in the environment, with ferrihydrite widely considered the most bioavailable phase. Yet, ferrihydrite is unstable and rapidly transforms to more crystalline Fe(III) oxides (e.g., goethite, hematite ...
Christopher J. Lentini, Scott D. Wankel, Colleen M. Hansel, Colleen M. Hansel   +3 more
doaj   +1 more source

A global view of shifting cultivation: Recent, current, and future extent [PDF]

, 2017
Mosaic landscapes under shifting cultivation, with their dynamic mix of managed and natural land covers, often fall through the cracks in remote sensing–based land cover and land use classifications, as these are unable to adequately capture such ...
Chini, Louise Parsons, Christensen, Andreas Egelund, Frolking, Stephen E., Hansen, Matthew, Heinimann, Andrew, Hurni, Kaspar, Hurtt, George, Mertz, Ole, Sahajpal, Ritvik, Sedano, Fernando   +9 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Cultivation of Watermelon (Citrullus lanatus (Tunb.)) in a Temperate Climate: Agronomic Strategies and Phytochemical Composition

Agronomy
This study investigates the phytochemical composition and cultivation strategies for watermelon (Citrullus lanatus (Thunb.)) in Lithuania’s temperate climate, focusing on its biological activity. Employing innovative grafting techniques and clear plastic
Deividas Burdulis, Aida Kašėtaitė, Sonata Trumbeckaitė, Raimondas Benetis, Jurgita Daukšienė, Kristina Burdulienė, Lina Raudonė   +6 more
doaj   +1 more source

Isolation, Description and Genome Analysis of a Putative Novel Methylobacter Species (‘Ca. Methylobacter coli’) Isolated from the Faeces of a Blackbuck (Indian Antelope)

Microbiology Research, 2021
Enteric fermentation of methane by ruminant animals represents a major source of anthropogenic methane. Significantly less information is available on the existence of methanotrophs in the gut of ruminants.
Kumal Khatri, Jyoti Mohite, Pranitha Pandit, Rahul A. Bahulikar, Monali C. Rahalkar   +4 more
doaj   +1 more source