Results 61 to 70 of about 403,258 (267)

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Cultivating trans-disciplinarity: transcending and transgressing research methods

Global Social Challenges Journal
Transdisciplinarity is creative human agency including cognitive, intellectual and behavioural activities of individuals and groups. These activities define and are mutually defined by beliefs and ideas, knowledge and know-how, language and meanings ...
Roderick J. Lawrence
doaj   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

Advanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu   +11 more
wiley   +1 more source

Planted Citrus Regulates the Community and Networks of phoD-Harboring Bacteria to Drive Phosphorus Availability Between Karst and Non-Karst Soils

Microorganisms
The phosphorus (P) availability in soils is influenced by microbes, particularly those containing the gene responsible for phosphate solubilization. The present study investigated the community structure, diversity, and co-occurrence networks of phoD ...
Xuan Yu, Lulu Feng, Yuan Huang, Yueming Liang, Fujing Pan, Wei Zhang, Yuan Zhao, Yuexin Xiao   +7 more
doaj   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Near-Infrared Spectroscopy for Growth Estimation of Spirulina platensis Cultures

Methods and Protocols
The present study proposes the use of Near-Infrared (NIR) spectroscopy as a rapid method for estimating the growth of Spirulina platensis cultures, avoiding any sample manipulation or pretreatment. NIR spectroscopy in diffuse reflectance mode was used on
Lamprini Malletzidou, Eleni Kyratzopoulou, Nikoletta Kyzaki, Evangelos Nerantzis, Nikolaos A. Kazakis   +4 more
doaj   +1 more source

The Cultivation of Trypanosomata [PDF]

Journal of Hygiene, 1905
Tr. Lewisi has been cultivated by me for nine generations, the duration of cultivation extending over a period of nine months. The culture is still alive and is now in its tenth generation. A culture of Tr. Brucei was cultivated through three generations for a period slightly exceeding eighty days. These cultural experiments, however, in no way compare,
openaire   +2 more sources

Leaftronics: Bio‐Fractal Scaffolds From Leaf Venation for Low‐Waste Electronics

Advanced Materials, EarlyView.
“Leaftronics” transforms naturally evolved leaf venation into quasi‐fractal scaffolds for sustainable electronics. Polymer‐infiltrated leaf skeletons can be used to fabricate ultra‐smooth, reflow‐ and thin‐film‐compatible decomposable substrates, while making the same lignocellulose networks conducting results in flexible transparent electrodes.
Rakesh Rajendran Nair, Hrisheekesh Thachoth Chandran, Karl Leo, Hans Kleemann   +3 more
wiley   +1 more source

Advancements and Prospects in Algal Biofuel Production: A Comprehensive Review

Phycology
Microalgae represent a valuable renewable resource for biofuel production due to their high lipid content, rapid growth rates, and non-competition with food resources.
Halina Falfushynska
doaj   +1 more source

The Diversity of Cultivation, Multi-Cultivation and Mixed-up Cultivation

Dānishhā-yi būmī-i Īrān, 2017
One of the more unknown wisdoms of the traditional agriculture and horticulture in the ancient civilizations which could invigorated agricultural fields for thousands years, probably, would be this diversity in cultivating different kinds of arable plants and trees in juxtaposed pieces (multi-cultivation), and co-cultivating arable plants in the same ...
openaire   +1 more source