Results 31 to 40 of about 46,420 (257)

HISTORY, MYTH AND ALLEGORY IN AUSTRALIAN CINEMA; pp. 276–286 [PDF]

Trames, 2008
How can historical fiction tell the truth about the past? Focusing on the disciplinary boundaries between history and cultural theory, this article argues that, at moments of national crisis, historical fiction has the capacity to produce new forms of ...
Felicity Collins
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Lev S. Vygotsky's cultural-historical theory and Soviet psychology of religion: did they overlap? [PDF]

Вестник Православного Свято-Тихоновского гуманитарного университета: Серия I. Богословие, философия
The paper examines the role played by one of the basic Marxist psychological theories in developing Soviet psychology of religion. An attempt is made to find out whether the cultural-historical theory of Lev S.
Alexey Dvoinin
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

ADHD Diagnosis from the Perspective of Cultural-Historical Neuropsychology

Культурно-историческая психология
The diagnosis of Attention-Deficit/Hyperactivity Disorder (ADHD) has been a subject of enduring debates, with numerous discussions challenging its validity and questioning the evidence that supports its existence.
A. Koutsoklenis, Y. Solovieva, L. Quintanar   +2 more
doaj   +1 more source

Using Cultural-Historical Theory to Explore Trauma among Refugee Populations in Europe

Культурно-историческая психология, 2018
The psychological impact of atrocities endured by refugee populations is clear, with the literature reporting significantly high prevalence rates of post-traumatic stress disorder (PTSD).
Womersley G.,, Kloetzer L.
doaj   +1 more source

Cultural-Historical Activity Theory in the Framework of the “Functional Paradigm”

Культурно-историческая психология, 2020
The aim of the paper is to highlight the peculiarity of the present state of the Cultural-historical activity theory (CHAT) in psychology, as compared to previous periods of its development in the general context of theory development in psychology.
Leontiev D.A.
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Is Cultural-Historical Activity Theory Threatened to Fall Short of its Own Principles and Possibilities as a Dialectical Social Science?

Outlines, 2006
In recent years, many researchers engaged in diverse areas and approaches of “cultural-historical activity theory” (CHAT) realized an increasing international interest in Lev S. Vygotsky’s, A. N. Leont’ev’s, and A. Luria’s work and its continuations. Not
Ines Langemeyer, Wolf-Michael Roth
doaj