Results 41 to 50 of about 46,420 (257)

Adopt a Cultural-Historical Perspective to Adapt Misinformation Interventions: Reflecting on Harjani et al.

Journal of Trial and Error
Harjani et al. (2023) conducted a gamified inoculation intervention against misinformation in rural India. Despite the ingenuity of the intervention design, the study revealed no significant effects on participants' ability to detect misinformation ...
Folco Panizza, Thomas Camminga, Stefan Gaillard, David Joachim Grüning   +3 more
doaj   +1 more source

Social Psychology of Development: Integrating the Ideas of L.S. Vygotsky and A.V. Petrovsky

Культурно-историческая психология, 2020
The article discusses the productivity — in terms of the further development of the cultural-historical tradition — of turning to social psychology, in particular, to the approach developed by A.V.
Tolstykh N.N.
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Transforming Mongolian Nursing Education: A Cultural–Historical Activity Theory Analysis of Historical Activity Systems

International Medical Education
Background: Nursing education has evolved in response to changing social, cultural, political, and healthcare contexts. Although Cultural–Historical Activity Theory (CHAT) has increasingly been applied in medical education research, its application to ...
Buyandelger Batmunkh, Munguntuul Enkhbat, Tuguldur Gankhuyag, Bat-Ulzii Enkh-Amgalan, Enkhbold Dogmidsangi, Oyungoo Badamdorj   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Cultural-Historical Theory and Social Psychology: A Nexus of Ideas

Вестник Московского университета. Серия 14: Психология
Background. The relevance of the stated topic is determined by two circumstances: the need to determine the main directions of the theoretical and methodological reflection of modern social psychology and the task of explaining the socio-psychological ...
Tahir Yu. Bazarov, Elena P. Belinskaya, Olga A. Tikhomandritskaya   +2 more
doaj   +1 more source

The Role of L.S. Vygotsky's Ideas in the Development of Social Cognition Paradigm in Modern Psychology: A Review of Foreign Research and Discussion on Perspectives

Культурно-историческая психология, 2015
The author reflects on the reasons for the increased interest of modern foreign social cognition researchers in L.S. Vygotsky's cultural-historical theory in the light of the existing methodological contradictions and recent empirical data.
A.B. Kholmogorova
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

New functionalism: rejuvenating historical and cultural heritage through urban revival

International Journal of Anthropology and Ethnology, 2019
The better protection and utilization of historical and cultural heritage sites, objects, and practices (especially intangible aspects of cultural heritage) based on anthropological research can work in the field of urban planning and design, an applied ...
Jijiao Zhang
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source