Results 61 to 70 of about 1,321,495 (304)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Культурно-историческая психология, 2015 The author reflects on the reasons for the increased interest of modern foreign social cognition researchers in L.S. Vygotsky's cultural-historical theory in the light of the existing methodological contradictions and recent empirical data.
A.B. Kholmogorova
doaj +1 more source
The Marked and the Magic in \u3cem\u3eProspero’s Daughter\u3c/em\u3e: Contextualizing Postmodern Witchcraft Accusations Using the Early Modern [PDF]
, 2019 Despite Prospero’s Daughter having won Elizabeth Nunez a handful of awards and having been received positively by critics, little aside from reviews about the novel exists in the literary sphere.
Gomez, Olivia
core +1 more source
Developing vocational practice in the jewellery sector through the incubation of a new “project-object” [PDF]
, 2008 This paper analyses a work placement scheme established to create the conditions to: (i) incubate new designs in the jewellery sector in Birmingham; (ii) support a jewellery company compete more effectively in the global market; (iii) assist a newly ...
Guile, David, Okumoto, Kaori
core +3 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Cultural-historical theory of psychological phenomena by L. S. Vygotsky
Культурно-историческая психологияThe fate of Lev Semyonovich Vygotsky’s psychological theory is quite extraordinary. The creator of one of the most original theoretical systems in psychology remained unknown to the wider international psychological community until quite
I. Ivic
doaj +1 more source
Social Practice Theory and the Historical Production of Persons [PDF]
, 2009 Working collaboratively we and others have developed a historical, material theory of social practice that integrates the study of persons, local practice, and long term historically institutionalized struggles.
Holland Dorothy, Lave Jean
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Cultural-Historical Theory and Social Psychology: A Nexus of Ideas
Вестник Московского университета. Серия 14: ПсихологияBackground. The relevance of the stated topic is determined by two circumstances: the need to determine the main directions of the theoretical and methodological reflection of modern social psychology and the task of explaining the socio-psychological ...
Tahir Yu. Bazarov +2 more
doaj +1 more source
Convergence and divergence dynamics in British and French business schools: how will the pressure for accreditation influence these dynamics? [PDF]
, 2013 This paper focuses on convergence and divergence dynamics among leading British and French business schools and explores how the pressure for accreditation influences these dynamics.
Ambrosini, V +3 more
core +3 more sources