Results 81 to 90 of about 1,321,495 (304)
Historical sociology, international relations and connected histories [PDF]
, 2010 This article addresses three recent developments in historical sociology: (1) neo-Weberian historical sociology within International Relations; (2) the 'civilizational analysis' approach utilized by scholars of 'multiple modernities'; and (3) the 'third ...
Bhambra, Gurminder K.
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Developing critical reading skills : a coursebook evaluation study [PDF]
, 2020 The aim of the paper is to discuss the importance of teaching critical reading skills, particularly in a foreign language context. The paper consists of two parts: theoretical and empirical.
Kusiak-Pisowacka, Monika
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Michael Cole as the Mediator and Integrator of Cultural-Historical Psychology
Культурно-историческая психология, 2018 The article describes the ideas and tuning points of M. Cole's career — the famous American psychologist, his theoretical, methodological and empirical contribution to modern psychology. It is composed of three sections.
Meshcheryakov B.G.,, Ponomarev I.V.,
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A Conceptual Model for Scholarly Research Activity [PDF]
, 2010 This paper presents a conceptual model for scholarly research activity, developed as part of the conceptual modelling work within the ???Preparing DARIAH??? European e-Infrastructures project.
Benardou, Agiatis +3 more
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The Psychological Content of Relationship between Sense and Meaning in Cultural-Historical Approach
Культурно-историческая психология, 2018 The paper considers L.S. Vygotsky’s cultural-historical theory and its interpretation in modern psychology. It shows that psychological content of many concepts introduced by L.S. Vygotsky differs greatly from that of the ones used in theory and practice
Kravtsova E.E., , Kravtsov G.G.,
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