Results 91 to 100 of about 3,418,859 (310)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A Study on Iranian Cultural Identity and Its transformations from the Perspective of the Scholars and People, in the Past Half Century [PDF]

open access: yesمسائل اجتماعی ایران, 2019
In this article, we seek to understand the common identity of Iranians and try to find out what cultural changes have embraced the popular mood of Iranian identity. In this study, the qualitative research method is based on the documentary analysis.
Ghorbanali Saboktakin rizi   +1 more
doaj  

Anos 80: Happenings poéticos na ‘era do estilo’

open access: yesRevista Crítica de Ciências Sociais, 2016
This study revisits a sandwich decade in Portugal’s contemporary history – the 1980s – which is still largely to be explored. The importance of the performing arts and experimental poetry within this transition period is identified and highlighted ...
Sandra Guerreiro Dias
doaj   +1 more source

Bridging cultural binaries through pedagogical practices [PDF]

open access: yes, 2013
In internationalising the curriculum, the move away from polarising domestic and international students to focus on preparing all students for global citizenship is promising.
Meerwald, A.M.L.
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A Forest of Blue - Canada's Boreal Forest, the World's Waterkeeper [PDF]

open access: yes, 2011
Describes how the lakes, rivers, and wetlands comprising the boreal forest preserve biodiversity, mitigate global climate change effects, and offer food and cultural benefits to rural communities.

core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The cultural change narrative as a core component of therapeutic change. [PDF]

open access: yesFront Psychiatry, 2023
Tobiassen AH   +3 more
europepmc   +1 more source

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