Results 231 to 240 of about 2,859,539 (300)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Cross-Cultural Adaptation of the EPICC Spiritual Care Education Standard Into European Portuguese. [PDF]

Scand J Caring Sci
Sitefane S, Afonso A, Alvarenga WA, Mcsherry W, Ross L, Attard J, Rabiais I, Caldeira S.   +7 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Perceived value and educational implications of traditional Chinese medicine nursing: a mixed-methods study. [PDF]

Front Public Health
Wang L, Zhang W, Wang Y, Wang H, Han Y, Wang X, Liu Y.   +6 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Multiple methods findings from a systematic scoping review and qualitative interviews to inform LGBTQ+ affirming practices for nursing education. [PDF]

Front Public Health
MacCarthy S, Valenti K, Beck A, Dancy L, Puga F, Bowen F.   +5 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Chatbot Usability Scale in Chinese Users: Cross-Cultural Adaptation and Validation Study.

JMIR Hum Factors
Ma H, Pei R, Li S, Wang A, Tang X, Piao M.   +5 more
europepmc   +1 more source

Cultural Competence in Nursing Care for Migrants: An Integrative Review. [PDF]

Int Nurs Rev
Arias JMV, Peres AM, Bustamante CAC, Serrato JT, Rico FME.   +4 more
europepmc   +1 more source