Results 101 to 110 of about 1,567,848 (355)

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

A focus on getting along: respect, caring and diversity [PDF]

open access: yes, 2016
Drawing inspiration om Joseph T. O’Connell’s work on socio‐cultural integration, this pa‐ per connects the notion of ‘deep equality’ with two broad lessons that can be taken om O’Connell’s approach that pertain to the study of religious diversity in ...
Beaman, Lori G.
core   +1 more source

Transformative Learning Through Cultural Immersion [PDF]

open access: yes, 2011
This qualitative study explored avenues to increase students’ intercultural competence through transformative learning. School of Education graduate students and faculty from a small, private university traveled to Ecuador to participate in a cultural ...
Addleman, Rebecca A.   +2 more
core   +3 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Effects of cultural diversity on individual establishments [PDF]

open access: yes
International immigration affects the degree of cultural diversity present in a labour force. This paper focuses on the consequences of immigration with respect to the level of cultural diversity by estimating employment functions for individual ...
Stephan Brunow, Uwe Blien
core   +3 more sources

Cities and Cultures [PDF]

open access: yes
We investigate the existence of wage premium due to cultural diversity across US cities. Using census data from 1970 to 1990, we find that at the urban level richer diversity is systematically associated with higher average nominal wages for white US ...
Gianmarco I.P. Ottaviano, Giovanni Peri
core  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Editorial. Design and Cultural Diversity

open access: yesFORMakademisk, 2019
By raising the theme of  Design and Cultural Diversity in this special issue of FormAkademisk we hope to stimulate a broad cross disciplinary discussion on the interplay of cultures within the field of design and design education.
Astrid Skjerven
doaj   +1 more source

Los Angeles County Arts Commission Cultural Equity and Inclusion Initiative Literature Review [PDF]

open access: yes, 2016
This literature review is intended to investigate and provide background information on how others have addressed the question of improving "diversity in cultural organizations, in the areas of their leadership, staffing, programming and audience ...
Bronwyn Mauldin   +3 more
core  

Examining 'window dressing' : the views of black police associations on recruitment and training [PDF]

open access: yes, 2007
In a previous issue of this journal, Ellis Cashmore (2002 Cashmore, E. 2002. ‘Behind the window dressing: minority ethnic police perspectives on cultural diversity’. Journal of Ethnic and Migration Studies, 28(2): 327–41.
Goodson A.   +8 more
core   +1 more source

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