Results 111 to 120 of about 2,011,690 (292)

A Cultural Tourism Strategy: Enriching Culture and Building Tourism in Buffalo Niagara [PDF]

open access: yes, 2005
Their continued dedication to the region\u27s cultural, arts and heritage organizations and the development of cultural tourism has been, and will continue to be, essential to attaining the vision of “A Cultural Tourism Strategy”.
Buffalo Niagara Cultural Tourism Initiative
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Indeliable exhibition: Yellow river boat (2018): Trap (2018) [PDF]

open access: yes, 2018
This exhibition is one of two that make up a cultural and artistic exchange project with Xi'an Art Museum, Xi'an City, Shaanxi Province, China; Waikato Museum, Hamilton, NZ; and Wintec researchers (Hamilton, NZ).
Williams, Gareth C. A.
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Social representations of national identity in culturally diverse societies [PDF]

open access: yes, 2015
The concept of identity, although quite recent in the social sciences (it was popularized by Erikson in the 1950s; see Gleason, 1983), is one of the few concepts to have been so widely studies and theorized. Psychologists, sociologists, anthropologists,
Andreouli, Eleni, Chryssochoou, Xenia
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Identidad escolar en las preparatorias de Nuevo León / School identity in Nuevo Leon preps [PDF]

open access: yesTransformación, 2016
Los procesos identitarios en la educación cobran interés científico dados los retos que acarrea el desarrollo del transporte y las comunicaciones, los cuales exponen a los jóvenes a continuas influencias de culturas foráneas.
Garza, Eric   +3 more
doaj  

Different coloured tears: Dual cultural identity and Tangihanga – A directed study [PDF]

open access: yes, 2010
Although whānau/family that are configured by both Pākehā and Māori identities number significantly within New Zealand, there has been little or no attention paid to the ways in which these identities influence the bereavement processes that will ...
Edge, Kiri, Nikora, Linda Waimarie
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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