Results 111 to 120 of about 1,795,391 (358)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Identidad escolar en las preparatorias de Nuevo León / School identity in Nuevo Leon preps [PDF]

open access: yesTransformación, 2016
Los procesos identitarios en la educación cobran interés científico dados los retos que acarrea el desarrollo del transporte y las comunicaciones, los cuales exponen a los jóvenes a continuas influencias de culturas foráneas.
Garza, Eric   +3 more
doaj  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Giving meaning to identities. A case-study for the Romanian Banat region [PDF]

open access: yes
This research is focussed on the ethnic identities from Banat maintained till nowadays under different cultural forms. Identity starts from the feeling of ‘social space’, with a specific language for each ethnic group and a specific culture evolving ...
Woudstra, Jaco
core   +1 more source

Negotiating the in-between : how two foreigners living in rural Japan narrated changes in their identities : a thesis presented in partial fulfilment of the requirements for the degree of Masters in Education (Guidance Studies), Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2009
This thesis used narrative inquiry to find out how two foreigners, who had resided in rural Japan for a long period of time, narrated reflectively how they had changed as a result of their cross-cultural transitions. This thesis came about through my own
Lankshear, Andrew
core  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

“La Bretagne aux Bretons?” : Cultural Revival and Redefinition of Brittany in Post-1945 France

open access: yes, 2013
A sense of national identity in France is something that has been defined and redefined throughout the twentieth century. With a history that includes two world wars, the creation of the European Union, in addition the the notable action of ...
Hornbeck, Gabriella L
core  

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