Results 61 to 70 of about 779,176 (289)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Critique of Creativity: Precarity, Subjectivity and Resistance in the ‘Creative Industries’ [PDF]

open access: yes, 2011
234 p. : il., Tablas.Libro ElectrónicoLa creatividad siempre está en movimiento: surge, se establece en el ente colectivo, palidece y desaparece a veces en el olvido; renace, vuelve con innovaciones, se reformula y resurge iniciando de nuevo el ciclo.
Raunig, Gerald (Ed.)   +2 more
core  

O sector económico da cultura na Área Metropolitana de Lisboa. Aspectos locativos e implicações nas políticas urbanas [PDF]

open access: yes, 2000
CULTURAL INDUSTRIES IN THE LISBON METROPOLITAN AREA: LOCATION FEATURES AND IMPLICATIONS ON URBAN POLICIES - This paper aims to examine the current situation and the recent development of cultural industries in the Lisbon Metropolitan Area in view of the ...
Eduardo Brito Henriques
core   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Are workers in the cultural industries paid differently? [PDF]

open access: yes, 2007
This paper aims to explore wage differentials between employees in three sub-industries of the cultural industries compared with the main (1-digit level) industry to which they belong.
Wetzels, Cecile
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Leaders Role Within Cultural Industries [PDF]

open access: yes
In the increasingly turbulent and competitive environment business, the dilemmas experienced by managers in cultural industries are characteristic to this type of industries where knowledge and creativity are key to sustaining competitive advantage ...
Cristina MANOLACHE, Radu CAMENITA
core  

Social network market: Storytelling on a web 2.0 original literature site [PDF]

open access: yes, 2011
This article looks at a Chinese Web 2.0 original literature site, Qidian, in order to show the coevolution of market and non-market initiatives. The analytic framework of social network markets (Potts et al., 2008) is employed to analyse the motivations ...
Anderson C.   +38 more
core   +3 more sources

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