Results 51 to 60 of about 1,442,299 (364)

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Date estimation of fabrication and repair of Color garments encouragement banner

Fashion and Textiles
The Color Garments Encouragement Banner was designated a Korean Heritage in 2014 to recognize it as the most significant object of the color garments encouragement campaign.
Seonghee Pak, Boyeon An, Changsang Yun
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Quantitative Evaluation of Digital Economy Policies in the Tourism Industry Using the TF-IDF and PMC Index Model

IEEE Access
With the acceleration of globalization, the development of the tourism industry increasingly relies on cross-border collaboration, and the digital economy can provide new opportunities for the tourism industry and promote the global application of new ...
Yu Xia
doaj   +1 more source

The rise of a new cultural products industry cluster in Germany : the case of the Leipzig media industry [PDF]

, 2005
Over the past decade, a variety of studies have shown that other sectors in addition to high technology industries can provide a basis for regional growth and income and employment opportunities.
Bathelt, Harald
core  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Analysis of Aspergillus niger isolated from ancient palm leaf manuscripts and its deterioration mechanisms

Heritage Science
Palm leaf manuscripts (PLMs), venerable historical artefacts containing Buddhist scriptures, history, mathematics and literature, which are carried by palm leaves (Corypha umbraculifera) and are highly susceptible to microbial degradation during ...
Shimin Chu, Lanying Lin, Xingling Tian
doaj   +1 more source

Cultural transformation in construction partnering projects [PDF]

, 2006
In recent years there has been a growing interest in the use of partnering in construction. Since partnering is seen as changing behaviours and attitudes, cultural transformation cannot be forgotten in the process.
Amaratunga, Dilanthi, Haigh, Richard, Thurairajah, N.   +2 more
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Correction: Gargalis et al. A Comparative Investigation of Duplex and Super Duplex Stainless Steels Processed through Laser Powder Bed Fusion. Metals 2023, 13, 1897

Metals
In the original publication [...]
Leonidas Gargalis, Leonidas Karavias, Joachim S. Graff, Spyros Diplas, Elias P. Koumoulos, Evangelia K. Karaxi   +5 more
doaj   +1 more source