Results 51 to 60 of about 83,750 (298)

A Systematic Review of Contemporary Challenges and Debates on Chinese Food Security: Integrating Priorities, Trade-Offs, and Policy Pathways

Foods
Although food security has been a long-standing focus of research and policy in China, significant gaps remain in synthesizing evolving debates across multiple disciplines such as agriculture, economics, environmental science, and politics.
Rong Zeng, Meseret C. Abate, Baozhong Cai, Amsalu K. Addis, Yonas Derebe Dereso   +4 more
doaj   +1 more source

Artists in Urban Regeneration Processes : Use and Abuse ?

Territoire en Mouvement, 2013
Interest in the role of culture within local economic development strategies has developed significantly both in academic and in policy-making circles since the 1980s. In recent years, one could testify a sort of ‘cultural fever’ among policy-makers and ‘
Mariangela Lavanga
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Décliner pour progresser : 25 stratégies multimédiatiques dans l’édition pour la jeunesse

Strenae, 2011
In order to make progress, children's publishers rely on three key elements: target audiences, brand development, and expanding the label through spin offs/audiovisuals.
Bertrand Ferrier
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Effective Product Development Framework to Examine Enterprise Organizational Learning

Tehnički Vjesnik
Intelligent Product Development of Industry 4.0, systematic and thorough study in Chinese circumstances is uncommon. It is a new idea that requires study progress for precise definitions and measures.
Ronglin Wu, Yuefeng Zhang
doaj   +1 more source

Cultural industries in public policy

Journal of International Studies, 2015
This paper focuses on cultural industries. They are becoming a part of culture on the national level because they create both the symbolic and the economic capital. The research proves that investment in cultural industries is beneficial; they help to attract tourists and investors from other countries, improve the image of the country and increase ...
openaire   +4 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

The Making of the Imaginary Value: Issues in the displacement of image of the Disney production [PDF]

Estudos em Comunicação, 2012
This paper analyzes the problem of displacement of image in the process of creating Disney comics and animation. The research seeks answers to issues of cultural production, especially the representation of the characters and their impact in the minds of
Celbi Vagner Melo Pegoraro
doaj  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source