Results 71 to 80 of about 83,750 (298)

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Culturas populares e identificações emergentes: Reflexões a partir do manguebeat e de expressões musicais brasileiras contemporâneas

open access: yesRevista Crítica de Ciências Sociais, 2008
This article analyses the interaction among several factors which, related to recent socio-cultural changes, contribute to the centrality of music and other forms of aesthetic expression in processes of re-articulating identities, within which we can ...
Luciana F. M. Mendonça
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Grup d’Estudis en Cultura i Societat (GRECS)

open access: yesDigithum, 2011
Aquest article explica l’aproximació al lligam entre cultura i societat que es treballa des del grup de recerca GRECS (Grup d’Estudis en Cultura i Societat).
Roger Martínez (coord.)
doaj   +1 more source

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