Results 41 to 50 of about 1,037,703 (310)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Two in vitro methods were tested to establish their potential to predict the metabolizable energy (ME) content of forage legumes: the Tilley and Terry (TT) method and the pepsin-cellulase method (CM). Different samples of white clover (Trifolium repens L.
Gierus Martin +5 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Tracing Cultural Landscape Values of Children with Participatory Geographic Information System
The cultural landscape value categories found from the workshop evaluation describe the character of the cultural landscape of children: living, learning and moving in the network of places between home and the world outside based on the local and family
Puolamäki Laura
doaj +1 more source
The presented paper reports data from malacological and pedological studies carried out at sites representing diverse biotopes (beech wood, coniferous forest, and meadow) located 2 km away from the Dyckerhoff Cement Plant in Sitkówka-Nowiny in 1992 and ...
Barga-Więcławska Jadwiga Anna +1 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Back to the boys? Temptations of the good gender theorist [PDF]
Saturated with gloom, anxiety, mirth or irony, discourses of men in crisis are ubiquitous. Critically surveying available empirical evidence and the ever-expanding conceptual apparatus for deconstructing and refiguring masculinities, this article ...
Segal, Lynne
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The fourth dimension in landscape analysis: changing of heritage and ecological values in the Évora cultural landscapes. [PDF]
Time is one of the most important driving forces in Landscape Ecology. Time along with geosystem, biosystem and socialsystem determines landscape heterogeneity which reveals itself in different patterns and functions.
Batista, Teresa +2 more
core
'Sarsen stones in Wessex': a society of antiquaries project contextualised and renewed [PDF]
This paper reviews the Society of Antiquaries’ Evolution of the Landscape project, which started in 1974, and the project’s Sarsen Stones in Wessex survey.
Ashbee +34 more
core +1 more source

