Results 51 to 60 of about 13,852,248 (340)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A CULTURAL LANDSCAPE INFORMATION SYSTEM DEVELOPED WITH OPEN SOURCE TOOLS [PDF]
ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2013 Abstract. Since 2010, the state of Rhineland-Palatinate in Germany has developed a cultural landscape information system as a process to secure and further enrich aggregate data about its cultural assets. In an open dialogue between governing authorities and citizens, the intention of the project is an active cooperation of public and private actors. A
C. Chudyk +3 more
openaire +3 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The Cultural Landscape & Heritage Paradox; Protection and Development of the Dutch Archeological-Historical Landscape and its European Dimension [PDF]
, 2010 To what extent can we know past and mainly invisible landscapes, and how we can use this still hidden knowledge for actual sustainable management of landscape’s cultural and historical values.
Kars, H. +3 more
core
Cultural Landscape Conservation: The Case of Mornington Peninsula, Australia
, 2022 One of the indelible qualities of a successful landscape plan, and thus, a designed landscape, is one that merges into the landscape and becomes the landscape itself.
Jones, DS
core +1 more source
Good Systems Network Meeting [PDF]
, 2020 You're viewing a past event from the Good Systems Grand Challenge team at The University of Texas at Austin that contains two presentations from May 19, 2020.Office of the VP for ...
Good Systems
core +1 more source
Many Perceptions, One Landscape [PDF]
, 2014 This paper relates an attempt to develop an integrated understanding of landscape values in the Akaroa Basin, in the South Island of New Zealand, as part of the author's PhD research. This case study sought to understand the landscape through the eyes of
Stephenson, Janet
core +1 more source
Humanities & Social Sciences CommunicationsRapid urbanization has led to the degradation of traditional water systems and the loss of associated landscape spaces, adversely affecting the sustainable development of coastal cities.
Can Yi, Haotian Ju, Ziqi Cui, Wei Guo
doaj +1 more source
Land, 2022 Agricultural activities play an important role in shaping landscape, in particular, in Lithuania, where agricultural land accounts for more than half of the surface land.
Lucia Rocchi +2 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source