Results 41 to 50 of about 138,952 (282)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Identities, Education and Reentry: Performative Spaces and Enclosures [PDF]
, 2014 This is part one of a two-part interdisciplinary paper that examines the various forces (discourses and institutional processes) that shape prisoner-student identities.
Wright, Randall
core +3 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Twenty years later: The war did (not) begin at Maksimir an anthropological analysis of the media narratives about a never ended football game [PDF]
Glasnik Etnografskog Instituta SANU, 2012 The aim of this work is an analysis of the media narratives about the never ended football match between Dynamo Zagreb and Red Star Belgrade on May 13 1990.
Đorđević Ivan
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Humanities & Social Sciences CommunicationsBased on the English-Chinese Parallel Corpus of Children’s Literature and the Corpus of Chinese Children’s Literature, this study investigates the feature of normalization in the Chinese translation of English children’s literature.
Yang Han
doaj +1 more source
Historical Evolution of Spatial Abilities
Behavioural Neurology, 1993 Historical evolution and cross-cultural differences in spatial abilities are analyzed. Spatial abilities have been found to be significantly associated with the complexity of geographical conditions and survival demands.
A. Ardila
doaj +1 more source
Silence and Denial in Everyday Life—The Case of Animal Suffering
Animals, 2011 How can we make sense of the fact that we live in a world where good people co-exist in silence about widespread animal suffering. How is it that sites of suffering such as laboratories, factory farms, abattoirs and animal transportation are all around ...
Deidre Wicks
doaj +1 more source
The Rise of the Austrian Freedom Party in the 1990s: A Culturalist Approach [PDF]
, 2009 NoDer Beitrag gibt einen Überblick über unterschiedliche wissenschaftliche Erklärungsansätze zum bemerkenswerten Aufstieg der FPÖ Jörg Haiders in den 1990er Jahren.
Murphy, Anthony J.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source