Results 91 to 100 of about 133,867 (296)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Responses to, and lessons learnt from, the January and February 2016 bushfires in remote Tasmanian wilderness

, 2016
This report examines the response to, and lessons learnt from, recent fires in remote Tasmanian wilderness affecting the Tasmanian Wilderness World Heritage Area.The introductory chapter outlines the history and effect of the bushfires that occurred
Senate Environment and Communications References Committee
core  

Intertextuality in A. Salnikov’s novel “Occulttreger”

RUDN Journal of Studies in Literature and Journalism
The features of the use of intertextual references in A. Salnikov’s novel “Occulttreger” are examined. The goal is to study the intertextual connections of the novel with works of various types of art (literature, music, cinema).
Daria L. Kulikova
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Submerged cultural resources study.

, 2001
"Publication was made possible through a donation from the Arizona Memorial Museum Association."Shipping list no.: 2001-0170-P."3rd printing, 2001"--P. iii.Includes bibliographical references (p.
Southwest Cultural Resources Center. Submerged Cultural Resources Unit., Lenihan, Daniel., Arizona Memorial Museum Association.   +2 more
core  

Affective Aesthetics: Mapping Visual Cultural Memories in the 2022 Anti-Zero-COVID Policy Protest in China

Lateral
This article examines the meaning‐making work of historical, cultural, and visual references in the 2022 anti-Zero-COVID policy protests in China. Characterized by homemade protest placards, the wave of 2022 grassroots protests were striking, typically ...
Chelsea Wenzhu Xu
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Translation Norms Of Cultural References From Arabic Into English In The Queue: An Analysis Using Newmark’s Cultural References And Toury’s Operational Norms [PDF]

The present study is primarily about the translation norms of cultural references from Arabic into English in Basma Abdelaziz's novel, The Queue. This particular novel was selected for analysis because it abounds with cultural references that mirror ...
Alharahsheh, Abdelrauof Meqbel Ah
core  

Traducción de referencias culturales en textos biomédicos sobre enfermedades neuromusculares (francés - español) [PDF]

Çédille: Revista de Estudios Franceses, 2015
Studies that focus on the translation of biomedical texts often do not address issues of cultural nature. However, references appear in these texts to specific aspects of the socio cultural context in which they are generated.
Elena Sánchez Trigo, Tamara Varela Vila
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source