CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
The Italian translation of culture-bound jokes and cultural references in American TV cartoons
P.L. Iaia
doaj +1 more source
Semantic convergence in culturally loaded text translation by Large Language Models: a cross-model empirical analysis of English translations of <i>The Four Books</i>. [PDF]
Wan Q, Yu Q.
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Current Landscape of Mental Health Conversational Agents From a Trauma-Informed Care Lens: Scoping Review. [PDF]
Kollig F +4 more
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Translating the Greek Gastronomic Cultural Element: Challenges and Strategies
This paper explores the linguistic, cultural, and pragmatic challenges involved in translating Greek gastronomic cultural elements into English. Greek cuisine, shaped by millennia of historical and social influences, constitutes a complex semiotic ...
Evanthia Saridaki
doaj
Cultural factors in mid- and later life volunteerism in the United States: A scoping review protocol. [PDF]
Lai PHL, White-Saul B, Su CY, Cao QK.
europepmc +1 more source
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
The EDIcebreaker: a new educational inclusive tool. [PDF]
Abou Nader N +5 more
europepmc +1 more source

