Results 171 to 180 of about 7,922,030 (338)

Crossing Cultures : German, Italian and French cross-cultural references

open access: yes, 2008
Lo studio Incrocio di culture analizza le differenze culturali comuni e reciproche − un approccio all’inter- culturalità − di tedeschi, italiani e francesi in materia di patrimonio architettonico, storico, letterario, cinemato- grafico, teatrale e lirico e sui riferimenti o le figure della cultura popolare. L’inchiesta è stata condotta su 4.500 persone
openaire   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Consumer Perceptions of Cultural Sustainability in Neo-Chinese Furniture: A Text Mining Analysis of Online Reviews from JD and Tmall

open access: yesBioResources
This study investigates how consumers perceive the cultural sustainability of Neo-Chinese furniture through the lens of online reviews on two major e-commerce platforms in China: JD.com and Tmall.
Yiming Chen, Yongmei Chen, Xinyou Liu
doaj  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Cultural References And Metaphors In Programming: The Symbolic Significance Of Variable Names And Comments In Code

open access: yesThe Journal of Studies in Language, Culture and Society
This paper investigates the symbolic significance of cultural references and metaphors in programming, focusing on their use in variable names and code comments.
Selma Mokrani
doaj  

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