Results 111 to 120 of about 871,084 (301)
African-Born Immigrants in U.S. Schools: An Intercultural Perspective on Schooling and Diversity
, 2011 Despite the significant increase of African-born immigrants in the United States of America, the education system does not recognize their presence and does little to facilitate their integration through the implementation of necessary curricular ...
Awokoya, Janet, Harushimana, Immaculee
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
No. 09: Comparing Household Food Security in Cities of the Global South through a Gender Lens [PDF]
, 2017 Understanding the determinants of urban food insecurity requires sensitivity to local cultural contexts and taking into account a globally relevant framework for analysis.
Caesar, Mary, Riley, Liam
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Results from an international awareness survey [PDF]
Business persons who engage in international commerce need to be aware that people differ in their perspectives around the world. We now take that as a “given” as the world becomes more globalized, but mistakes are made and managers are sent back home ...
James K. McCollum
core
Towards international cultural diversity management of public relations: viewpoints of chairmen/CEOs [PDF]
, 2007 This paper aims to promote a better understanding of how cultural diversity is practised in multinational corporations in Malaysia. Cultural diversity considers a complex element of management facets within the corporate culture.
Abdullah, Zulhamri
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Cultural sensitivity in health promotion program: Islamic persuasive communication [PDF]
, 2008 Although scenarios in global health are witnessing benefits from new medicines and technologies, nonetheless there are unprecedented reversals. As a result, the World Health Organization has encouraged more innovative approaches in promoting health risk ...
Ahmad, Mohd Khairie +2 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source