Results 121 to 130 of about 871,084 (301)

Culturally Sensitive Perinatal Mental Health Care: Experiences of Women From Minority Ethnic Groups

Health Expectations
Background Current research has identified how ethnic minority women experience poorer health outcomes during the perinatal period. In the United Kingdom, specialist perinatal mental health services provide mental health treatment for women throughout ...
Angelene Gardner, Sheri Oduola, Bonnie Teague   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Beyond supermarkets: ethnic stores, food environments, and the limits of the Food Access Research Atlas

Frontiers in Public Health
BackgroundThe Food Access Research Atlas (FARA) is a nationally used measure for community food environment that informs resource allocation to improve food access and population health.
Rujia Xie, Rujia Xie
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Governing Diversity at the Frontline: The Dual Logics of Cultural Sensitivity and Assimilation in Sweden

Nordisk Välfärdsforskning
This article investigates how street-level bureaucrats (SLBs) in Sweden manage cross-cultural challenges in their everyday interactions with migrants.
Andrea Spehar
doaj   +1 more source

The Light We Shine into the Grey: A Restorative #MeToo Solution and an Acknowledgement of Those #MeToo Leaves in the Dark [PDF]

, 2019
In the past year and a half, American women have publicly discussed experiences of sexual assault, harassment, and—notably—grey-area misconduct in an unprecedented manner.
Stewart, Nora
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

CULTURAL SENSITIVITY IN AI TRANSLATION OF CHINESE LANGUAGE: EVALUATING AI’S CAPABILITY TO GRASP CULTURALLY RICH TEXTS

Studia Universitatis Babeş-Bolyai. Philologia
Cultural Sensitivity in AI Translation of Chinese Language: Evaluating AI’s Capability to Grasp Culturally Rich Texts. The widespread adoption of Artificial Intelligence (AI) in translation has fundamentally reshaped global communication by enhancing ...
Iulia Elena CÎNDEA, Jiong WANG
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Nursing in a multicultural world: Cultural competence and sensitivity as ethical imperatives

Annals of Tropical Research
Healthcare today is marked by growing cultural diversity, which profoundly shapes the way nurses deliver care. This perspective article argues that cultural competence and cultural sensitivity are not optional skills but essential dimensions of effective
France Allan Cavite
doaj   +1 more source