Results 31 to 40 of about 46,539 (267)
ÎNTRE IDENTITATEA NAŢIONALĂ ŞI IDENTITATEA EUROPEANĂ
EIRP Proceedings, 2008 The context of european integration resulted in numerous questions and controversesregarding maintaining the national identity of each nation, once i twill obtain the membership of the EuropeanUnion.Many states saw this process as giving up the ...
Gina Livioara Goga
doaj
Le tradizioni della cultura orale e scritta (traduzione di Noemi Albanese)
eSamizdat, 2023 Italian translation of Traditsii ustnoi i knizhnoi kul’tury by Sergey Neklyudov.
Sergej Nekljudov
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Revue Internationale d’Éducation de Sèvres, 2021 This paper focuses on “obedience” as a traditional Chinese value. In the health sector, obedience was manifested in public cooperation with government control during the Covid-19 crisis, which enabled a restoration of public health security within months
Ora Kwo, Mingrui Yang
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Cumulative culture and complex cultural traditions [PDF]
Mind & Language, 2020 Cumulative cultural evolution is often claimed to be distinctive of human culture. Such claims are typically supported with examples of complex and historically late‐appearing technologies. Yet by taking these as paradigm cases, researchers unhelpfully lump together different ways that culture accumulates.
openaire +2 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
WHEN CULTURE MEETS RELIGION: THE MULUDAN TRADITION IN THE KA-NOMAN SULTANATE, CIREBON, WEST JAVA
Al-Albab, 2013 This article is based on a fundamental question, what is the relationship between practicing the Muludan tradition and seeking of power by the Royal family of the Kanoman Sultanate in Cirebon? The Muludan is a tradition conducted by the Royal family, and
Mohamad Yusuf
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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