Results 51 to 60 of about 2,133,258 (309)
Effects of pharmaceutical wastes on growth of microalgae [PDF]
, 1970 The purpose of this work was to assay samples of waste material from Puerto Rican pharmaceutical industries for inhibition of growth of algae. Two samples (noted as I and II) supplied to us were tested for toxicity to six microalgae.
Batterton, John +1 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo [PDF]
, 2017 While the use of bioluminescent proteins for molecular imaging is a powerful technology to further our understanding of complex processes, fluorescent labeling with visible light fluorescent proteins such as GFP and RFP suffers from poor tissue ...
Blyth, Karen +11 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
BarekengHigher education institutions depend on leadership to build their organizational culture and achieve better employee performance. However, there remains limited understanding of how the impact of leadership may vary across institutional contexts.
Hairur Rahman +5 more
doaj +1 more source
Effects of A Voltage Sensitive Calcium Channel Blocker and A Sodium-Calcium Exchanger Inhibitor on Apoptosis of Motor Neurons in Adult Spinal Cord Slices [PDF]
Cell Journal, 2012 Objective: The apoptosis of motor neurons is a critical phenomenon in spinal cord injuries. Adult spinal cord slices were used to investigate whether voltage sensitive calcium channels and Na+/Ca2+ exchangers play a role in the apoptosis of motor neurons.
Hamid Reza Momeni, Mahsa Jarahzadeh
doaj
The challenges of cross-cultural research and teaching in family medicine: How can professional networks help? [PDF]
, 2016 Modern medical training emphasizes the value of understanding the patient’s ideas, concerns and expectations, and the use of their personal perspective to assist communication, diagnosis, and uptake of all appropriate health and treatment options.
Howe, Amanda
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The development of culturally-sensitive measures for research on ageing [PDF]
Ageing and Society, 2011 ABSTRACTAttempts to import existing measures developed in other countries when constructing research instruments for use with older people can result in several problems including inappropriate wording, unsuitable response sets, and insufficient attention to cultural nuances.
openaire +2 more sources
Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition [PDF]
, 2016 EZH2 inhibitors have gained great interest for their use as anti-cancer therapeutics. However, most research has focused on EZH2 mutant cancers and recently adverse effects of EZH2 inactivation have come to light.
Bounova, Gergana +6 more
core +1 more source