Results 91 to 100 of about 8,036,181 (403)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

MANAGEMENT APPROACHES FOR INDUSTRY 4.0 – THE ORGANIZATIONAL CULTURE PERSPECTIVE

open access: yesTechnological and Economic Development of Economy, 2018
The Industry 4.0 concept describes a decentralized production chain that extends from design to the supply chain, production, distribution as well as customer service.
Hana Mohelská, M. Sokolová
semanticscholar   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Kişiselleştirme İllüzyonu ve Özgürlük Yanılsaması: Kültür Endüstrisi Bağlamında Talebe Bağlı Video Platformlarının İncelemesi

open access: yesMedya ve Kültür, 2021
Bu çalışmada talebe bağlı dijital video platformları, Adorno ve Horkheimar tarafından “kültür endüstrisi” terimi ile kavramsallaştırılan eleştirel yaklaşım üzerinden ele alınmıştır.
Fatih Saraç
doaj  

Cultural industries in public policy

open access: yesJournal of International Studies, 2015
This paper focuses on cultural industries. They are becoming a part of culture on the national level because they create both the symbolic and the economic capital. The research proves that investment in cultural industries is beneficial; they help to attract tourists and investors from other countries, improve the image of the country and increase ...
openaire   +4 more sources

Pleasure, profit and pain: Alcohol in New Zealand and the contemporary culture of intoxication [PDF]

open access: yes, 2013
This book details the rich, complex and often contested role of alcohol in New Zealand society. It explores the three fundamental alcohol rights that continue to fight for dominance of the national drinking culture: the rights of individual drinkers to ...
Campbell, Maxine M.   +3 more
core   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Marine shrimp culture industry of Thailand: operating guidelines for shrimp farms. [PDF]

open access: yes, 2005
The marine shrimp industry in Thailand had developed a code of conduct for its operations. This code of conduct is a set of principles and processes that provides a framework to meet the industry’s goal for environmental, social, and economic ...
Boyd, Claude E.   +4 more
core   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

The sociality of cultural industries

open access: yesInternational Journal of Cultural Policy, 2005
In this article, I explore the sociality of cultural industries by analyzing the film industry in Hong Kong. In particular, the social networks and relationships at multiple scales – across national boundaries, within local settings and on production sets – are examined, revealing their critical role in contributing to the health of the film industry ...
openaire   +4 more sources

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