Results 51 to 60 of about 312,868 (309)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Purkinje cell maturation participates in the control of oligodendrocyte differentiation: role of sonic hedgehog and vitronectin. [PDF]

PLoS ONE, 2012
Oligodendrocyte differentiation is temporally regulated during development by multiple factors. Here, we investigated whether the timing of oligodendrocyte differentiation might be controlled by neuronal differentiation in cerebellar organotypic cultures.
Lamia Bouslama-Oueghlani, Rosine Wehrlé, Mohamed Doulazmi, Xiao Ru Chen, Fanny Jaudon, Yolande Lemaigre-Dubreuil, Isabelle Rivals, Constantino Sotelo, Isabelle Dusart   +8 more
doaj   +1 more source

Concise review on clinical applications of conditioned medium derived from human umbilical cord-mesenchymal stem cells (UC-MSCS) [PDF]

, 2018
In recent years, mesenchymal stem cells have provoked much attentiveness in the field of regenerative medicine because of their differentiation potential and the capability to facilitate tissue repair via the emancipation of biologically active molecules.
Banerjee, Antara, Di Liddo, Rosa, Gopinath, Madhumala, Jothimani, Ganesan, Marotta, Francesco, Murugesan, Ramachandran, Pathak, Surajit, Sriramulu, Sushmitha   +7 more
core  

Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response. [PDF]

, 2016
Adipocytes promote cancer progression and impair treatment, and have been shown to protect acute lymphoblastic leukemia (ALL) cells from chemotherapies. Here we investigate whether this protection is mediated by changes in oxidative stress.
Behan, James W, Heisterkamp, Nora, Ji, Lingyun, Mittelman, Steven D, Parmentier, Jean-Hugues, Sheng, Xia, Tucci, Jonathan   +6 more
core   +1 more source

Erythropoietic activity in culture media conditioned by rat mesangial cells.

The Tohoku Journal of Experimental Medicine, 1989
Using a tissue culture technique we examined erythropoietin (EPO) producing cells in rat glomeruli. In 5 out of 6 independent glomerular cell cultures, EPO activity was found in the mesangial-cell proliferating phase, but not in the epithelial-cell proliferating phase. Therefore, mesangial cells seemed to be EPO producing cells.
Y, Fukushima, M, Yanagisawa, T, Yasuda, Y, Nakamoto, A B, Miura   +4 more
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Toxicity of Orthodontic Brackets Examined by Single Cell Tracking

Toxics, 2022
Subtle toxic effects may be masked in traditional assays that average or summate the response of thousands of cells. We overcome this by using the recent method of single cell tracking in time-lapse recordings.
Morgan Wishney, Swarna Mahadevan, James Anthony Cornwell, Tom Savage, Nick Proschogo, M. Ali Darendeliler, Hans Zoellner   +6 more
doaj   +1 more source

Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived fas ligand [PDF]

, 2005
Activated microglia may be detrimental to neuronal survival in a number of neurodegenerative diseases. Thus, strategies that reduce microglial neurotoxicity may have therapeutic benefit.
Jones, F, Kubota, ESFCS, Pocock, JM, Taylor, DL   +3 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

PRODUCTION OF BACTERIAL NANOCELLULOSE IN ALTERNATIVE CULTURE MEDIA UNDER STATIC AND DYNAMIC CONDITIONS

Latin American Applied Research - An international journal, 2023
Bacterial nanocellulose (BNC) was produced in three different culture media: the standard HS medium, and the alternative much less costly analytical glycerol/corn steep liquor (AG-CSL) and glycerol remaining from biodiesel production/corn steep liquor (BG-CSL) media.
Fernandez Corujo, Victoria Lilian, Arroyo, Silvana Maricel, Cerrutti, Patricia, Foresti, María Laura   +3 more
openaire   +2 more sources