Results 41 to 50 of about 1,751,397 (315)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Handling culture medium composition for optimizing plant cell suspension culture in shake flasks

open access: yes, 2017
This work aimed to optimize statistically the culture medium composition for cell plant suspension culture using as a model Capsicum baccatum L. var. pendulum cells.
Tiago Fidemann   +19 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Development of a Low-Cost and High-Efficiency Culture Medium for Bacteriocin Lac-B23 Production by Lactobacillus plantarum J23

open access: yesBiology, 2020
At present, De Man, Rogosa and Sharpe (MRS) broth is the medium of choice for promoting bacteriocin production. However, this medium is expensive and not applicable for large-scale production.
Jianming Zhang   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

FIBRIN AND SERUM AS A CULTURE MEDIUM [PDF]

open access: yesJournal of Experimental Medicine, 1921
A technique is described by which a medium composed of fibrinogen suspension, serum, and embryo juice may be made. Fibroblasts grew in this medium about as well as in plasma and embryo juice. A strain of connective tissue in this medium remained practically as active as the control for several passages.
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Desempenho de diferentes estádios embrionários no cultivo in vitro de embriões de 'Pêra Rio' x 'Poncã' Perfomance of different embryo stage of sweet orange x mandarin cultivated in vitro

open access: yesRevista Brasileira de Fruticultura, 2003
Objetivou-se verificar qual o melhor estádio embrionário para o cultivo de embriões imaturos oriundos de frutos provenientes de hibridação entre 'Pêra Rio' x 'Poncã' , bem como o efeito de diferentes concentrações do meio de cultura MT.
Edvan Alves Chagas   +6 more
doaj   +1 more source

RESPONSES OF SOME NEW ROMANIAN POTATO VARIETIES TO THE IN VITRO HIDRIC STRESS

open access: yesAgricultura, 2021
Plant performance and crop yield are negatively affected by drought and heat in the context of the global climate changes. The present study was carried out to the National Institute for Research and Development Brasov, Romania, to observe the ...
Manuela Hermeziu   +2 more
doaj   +1 more source

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