Results 171 to 180 of about 9,624,744 (303)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Diversity of ER-positive and HER2-negative breast cancer stem cells attained using selective culture techniques. [PDF]

open access: yesSci Rep
Sueoka S   +10 more
europepmc   +1 more source

Bulletin de l'équipe “Techniques, milieu et culture”

open access: yes, 2012
Lemonnier, Pierre   +2 more
core   +1 more source

"Ce que l’on détruit à Palmyre", Vincent Négri à réécouter sur France Culture

open access: yes, 2015
Avant-hier, Vincent Négri et Nada Al-Hassan étaient les invités des Nouvelles vagues sur France Culture pour évoquer la destruction des sites patrimoniaux en Syrie.
Droit, patrimoine & culture
core  

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

The detection of candida by the impression culture technique and the imprint culture technique.

open access: yesNihon Hotetsu Shika Gakkai Zasshi, 1985
Tamamoto, Mitsuhiro   +2 more
openaire   +2 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

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