Results 61 to 70 of about 15,620,197 (326)

Three-dimensional in vitro culture models in oncology research

open access: yesCell & Bioscience, 2022
Cancer is a multifactorial disease that is responsible for 10 million deaths per year. The intra- and inter-heterogeneity of malignant tumors make it difficult to develop single targeted approaches.
Camille Jubelin   +8 more
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Use of mangroves for aquaculture: Myanmar. [PDF]

open access: yes, 2004
Aquaculture has only started to develop rapidly in the past few decades, due to better knowledge of culture species, improved methodologies and techniques in breeding, nutrition and increasing demand for food fish of high-value species such as shrimps ...
Win, U Tin
core   +1 more source

New techniques to characterise the vaginal microbiome in pregnancy [PDF]

open access: yes, 2016
Understanding of the vaginal microbiome in health and disease is essential to screen, detect and manage complications in pregnancy. One of the major complications of pregnancy is preterm birth, which is the leading world-wide cause of death and ...
Kaakoush, N, Mendz, G, Quinlivan, J
core   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Exploring Culture-Specific Learning Styles in Accounting Education

open access: yes, 2015
Purpose – The purpose of this paper is to review whether culture affects accounting students’ learning processes to identify practical guidance for accounting educators facing a culturally diverse classroom. In spite of a significant literature thread in
Sauerwein, Joshua, Sikkema, Seth E.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Techniques of producing monosex or sterile population of fish for aquaculture -- a review of selected literature [PDF]

open access: yes, 1993
The need to develop techniques that can make the male grow faster in many species of fish as well as the female in some other species cannot be over-emphasized.
Aluko, P.O.
core  

An Modified Primary Culture Method of Breast Cancer-associated Fibroblasts

open access: yesZhongliu Fangzhi Yanjiu, 2018
Objective To establish a rapid and high efficient method of primary culture of BCAFs by improving primary culture methods of common breast cancer-associated fibroblasts (BCAFs).
LI Zhiyong, BAI Xue, CAI Huiyun
doaj   +1 more source

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