Results 81 to 90 of about 9,624,744 (303)

L\u27enseignement supérieur Culture - 2018-2019 [PDF]

L\u27enseignement supérieur Culture désigne le réseau constitué d\u27une centaine d\u27établissements d\u27enseignement (pour la plupart publics) dans les domaines de l\u27architecture, du patrimoine, des arts plastiques et du design, du spectacle vivant,
Ministère de la Culture
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Determination of bioactive and anti-inflammatory molecules of Thymbra spicata L. from Mardin by GC–MS and LC–Orbitrap HRMS: a DFT, molecular docking, ADMET, biological target and activity study

BMC Complementary Medicine and Therapies
Objectives In this study, phenolic compounds (PC), volatile compounds (VC), antioxidant, anti-inflammatory, and antimicrobial properties of the Thymbra spicata L. plant grown in the Mardin Yeşilli region were investigated.
Velid Unsal, Leyla Ercan, Cemile Gunbegi Calıskan   +2 more
doaj   +1 more source

L’Étude des systèmes techniques [PDF]

, 2011
La technologie culturelle est la branche de l’ethnologie qui traite des systèmes techniques. Qu’est-ce à dire ? Plus que par des définitions aussitôt contestables ou un programme de travail impossible à tenir, c’est en relation avec une recherche ...
Lemonnier, Pierre
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Characterization of zinc oxide and iron oxide nanoparticles stabilized with morin hydrate, and investigation and comparison of their antioxidant, antimicrobial, apoptotic, and anticarcinogenic properties

Discover Nano
This study aimed to synthesize and characterize morin hydrate-stabilized ZnO and FeO nanoparticles and to compare their antioxidant, antimicrobial, apoptotic, and anticarcinogenic properties in in vitro models.
Velid Unsal, Leyla Ercan, Cemile Gunbegi Calıskan   +2 more
doaj   +1 more source

Les techniques dans la pensée narrative [PDF]

, 2007
Toutes les formes de narration, des plus anciennes aux plus récentes, font une place aux techniques. Car celles-ci font partie des éléments que toute histoire doit emprunter au réel pour trouver des auditeurs ou des spectateurs intéressés. Mais il existe
Sigaut, François
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Les techniques, entre tradition et intention [PDF]

, 2007
Bien qu’unanimement admise par les chercheurs concernés, la définition des techniques donnée par Marcel Mauss recèle un défaut que les recherches contemporaines rendent de plus en plus apparent et qui, par conséquent, ne peut manquer de devenir ...
Guille-Escuret, Georges
core   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source