Results 101 to 110 of about 9,624,744 (303)
Jurnal Ilmiah Perikanan dan Kelautan, 2012 One type of phytoplankton that are used in marine fish hatchery activities namely Nannochloropsis oculata. The purpose of study case is to know patterns growth of N. oculata in culture scale laboratory, intermediate, and bulk. Study was held in Situbondo
Abdul Manan, Indah Permata Sari
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
The evolving paradigm of organoids: advances in cell line-derived organoids with 3-dimensional printing and emerging technologies [PDF]
OrganoidOrganoid research has rapidly emerged as a prominent field within the life sciences, particularly in biomedical research. Stem cells represent the primary source of human organoids due to their exceptional ability to reproduce organ-specific functions ...
Hyungjin Mun, Min Heui Yoo
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Histoire de l’art et anthropologie des techniques. Objets, processus, représentations [PDF]
, 2019 Si les termes « outil » et « instrument » ont en commun la désignation des objets que les humains fabriquent en vue d’exécuter une ou plusieurs tâches, ils répartissent néanmoins ces dernières en deux champs d’activités distincts.
Philippe Cordez, Cordez, Philippe
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
FP 09. Techniques d’enrayage [PDF]
, 2020 © Elzazimut La détérioration des conditions d’exercice de l’enseignement et de la recherche a entraîné un cortège de protestations internationales, faites de pétitions, de démissions et d’ouvrages ou articles critiques. Tout cela sans grand succès.
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Culture-Negative Peritonitis and the Latest Diagnostic Techniques
Kidney DiseasesBackground: Peritonitis is a common and serious complication of peritoneal dialysis that results in considerable morbidity, mortality, and increased healthcare costs.
Jiajia Ye +7 more
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Application of different techniques for garlic tissue culture initiation [PDF]
AgroznanjeGarlic (Allium sativum L.) is a vegetatively propagated crop of high nutritional, medicinal, and economic importance, nonetheless its conventional conservation in the field is limited by pathogen accumulation and genetic instability.
Kajkut Zeljković Mirela +6 more
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