Results 111 to 120 of about 2,691,981 (308)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Application of In Vitro Plant Tissue Culture Techniques to Halophyte Species: A Review. [PDF]

open access: yesPlants (Basel), 2022
Custódio L   +9 more
europepmc   +1 more source

Hydroponics or Soilless Culture [PDF]

open access: yes
Historically, hydroponics is not a new field; plant physiologists have known and used it for some 100 years. Inevitably, some enthusiasts got carried away.Claims were made of enormous potential yields; skyscraper tops were said to be capable of producing
Chapman, H. D.
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Effets de champignons MA sur la croissance et le développement de plants de ricin élevés sous contrainte saline en conditions semi-contrôlées

open access: yesRevue des Énergies Renouvelables, 2016
Contexte- La salinité constitue un des principaux facteurs abiotiques limitant la croissance et le rendement des espèces végétales. Les champignons Mycorhizes Arbusculaires, ‘MA’ peuvent réduire les pertes de rendement des végétaux soumis au stress salin.
B. Diallo, S.A.N. Samba, D. Sane
doaj  

Patient-derived three-dimensional culture techniques model tumor heterogeneity in head and neck cancer. [PDF]

open access: yesOral Oncol, 2023
Parikh AS   +10 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Controlled environment life support system: Growth studies with potatoes [PDF]

open access: yes
Results of experiments conducted to maximize the productivity of potatoes grown under controlled environmental conditions are discussed. A variety of parameters is examined which affect potato growth, specifically, photoperiod, light intensity ...
Tibbitts, T. W., Wheeler, R. M.
core   +1 more source

Aquaculture development in Thailand [PDF]

open access: yes, 1988
Aquaculture practised in Thailand is in the form of pond culture and cage culture in freshwater, brackishwater and coastal areas. The main species cultured include freshwater prawns, brackishwater shrimp, cockles, mussels, and various freshwater and ...
Chaiyakam, Kanit   +3 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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