Results 91 to 100 of about 9,624,744 (303)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Materiales para la Historia del Deporte, 2015 francesa. Con el fin de revelar las representaciones de juegos en este tipo de literatura infantil, este estudio analizará los "Juegos Olímpicos", serie de cuatro álbumes (Bibi Fricotin, Les Pieds Nickelés, Astérix y los Pitufos), que tuvieron mucho ...
Christian Vivier +2 more
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Mondes infimes sur France Culture
, 2018 Cette image illustre l'article d'Ashveen Peerbaye, « Altérations génomiques. Ce que le diagnostic moléculaire fait au cancer », Techniques&Culture 68 « Mondes infimes », p. 214-229.
techniquesetculture
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Risk culture in financial organisations [PDF]
, 2013 Interest in the cultures of organisations and their effects on management practices goes back many years and there is an extensive body of scholarship on this topic. Yet this interest has increased dramatically in the period since 2008. The debate is led
Power, Michael +2 more
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La culture matérielle, la numérisation et le problème de l’artefact [PDF]
, 2012 La culture matérielle, la numérisation et le problème de l’artefact. Les récentes innovations dans le domaine de la numérisation de la fabrication d’objets posent de nouvelles questions concernant notre conception de la nature de l’artefact. Elles posent
Buchli, Victor
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
CeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2019 Conservation training is much influenced by the culture context in which it is developed. Depending on the country of origin, structural treatment of canvas paintings widely varies, reflecting climate conditions but also training traditions.
Maria Aguiar +5 more
doaj +1 more source
, 2005 Entre le corps et les techniques se joue une dialectique complexe : l’homme produit le milieu qui l’entoure; la nature et la culture exercent à leur tour des contraintes sur les savoirs et savoir-faire ainsi que sur les représentations sociales.
Lacombe, Philippe
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Medical Laboratory Journal, 2022 Background and objectives: Developing scaffolds is important for tissue engineering and repairing damaged tissues. The present study aimed to investigate effects of pre-incubation of an electrospun silk fibroin scaffold in complete and serum-free media ...
Maryam Janitermi +2 more
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