Results 101 to 110 of about 968,871 (386)

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Systematic free energy insights into the enhanced dispersibility of myofibrillar protein in low-salt solutions through ultrasound-assisted enzymatic deamidation

Ultrasonics Sonochemistry
This work aimed to investigate the effects of ultrasound assisted enzymatic deamidation by protein-glutaminase (PG) on the dispersion of myofibrillar protein (MP) in low-salt solutions.
Yating Liu, Zongyun Yang, Zhen Li, Juan Shen, Xia Wang, Ru Li, Ye Tao, Xinglian Xu, Peng Wang   +8 more
doaj   +1 more source

The History, Present Condition, and Future of the Molluscan Fisheries of North and Central America and Europe: Volume 3, Europe [PDF]

, 1997
(PDF file contains 248 pages.
Burrell, Jr., Victor G., Hobart, Willis L., MacKenzie, Jr., Clyde L., Rosenfield, Aaron   +3 more
core  

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Hyperspectral guidance for summer tea processing: Enhancing taste and aroma through short‐term cycled heaping

Food Frontiers
To reduce the unpleasant flavor in tea infusion made from summer fresh leaves and lessen tea resource wastage, a short‐term cycled heaping method, addressing the temperature/moisture variations during prolonged heaping, was introduced to produce high ...
Hujing Cao, Jingjing Tian, Jiarui Zeng, Yujing Wu, Shuofei Xu, Yu Duan, Tingting Shen, Leiqing Pan, Zhihong Xin, Wanping Fang, Xujun Zhu   +10 more
doaj   +1 more source

Ultrasonic-Assisted tumbling improves water retention and tenderness of wooden breast chicken meat

Ultrasonics Sonochemistry
Wooden breast myopathy results in reduced meat tenderness, poor water retention, and diminished processing value, underscoring the urgency to mitigate economic losses caused by the deteriorated quality of wooden chicken breast.
Yanyan Lu, Zhenyang Wu, Tianjiao Bian, Xue Zhao   +3 more
doaj   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

miR124a-3p inhibitor alleviates AFB1-induced hepatoxicity via targeting chicken glucocorticoid receptor mRNA

Poultry Science
Glucocorticoid receptor (GR) plays crucial roles in various processes, including stress response, inflammatory response and toxin response, making it a therapeutic target for numerous diseases.
Mindie Zhao, Liang Chen, Yulan Zhao, Jie Liu, Huimin Chen, Ruqian Zhao   +5 more
doaj   +1 more source

Muxama and other traditional food products obtained from tuna in south Portugal and Spain: review and future perspectives [PDF]

, 2020
There is evidence that consumers perceive fish as healthy (Carlucci D et.al, Appetite 84:212–27,2015; Vanhonacker F et.al, Br Food J 115:508–25,2013; Verbeke W et.al, Public Health Nutr 8:422–9,2005.).
Aníbal, J., Esteves, Eduardo
core  

An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring

Advanced Science, EarlyView.
Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar, Marc A. Fernandez‐Yague, Adrien Bessaguet, Hosoowi Lee, Nicolas Giuseppone, Andrés J. García, Aránzazu del Campo   +6 more
wiley   +1 more source