Results 51 to 60 of about 965,886 (297)

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Establishment of cumulative assessment groups of pesticides for their effects on the nervous system

EFSA Journal, 2019
Cumulative assessment groups of pesticides have been established for five effects on the nervous system: brain and/or erythrocyte acetylcholinesterase inhibition, functional alterations of the motor, sensory and autonomic divisions, and histological ...
European Food Safety Authority (EFSA), Federica Crivellente, Andy Hart, Antonio F Hernandez‐Jerez, Susanne Hougaard Bennekou, Ragnor Pedersen, Andrea Terron, Gerrit Wolterink, Luc Mohimont   +8 more
doaj   +1 more source

Spatial Dependence Analysis of Weekly Moving Cumulative Rainfall for Flood Risk Assessment

Atmosphere, 2023
Climate change has intensified the frequency and severity of extreme weather events, necessitating a nuanced understanding of flood patterns for effective risk management. This study examines flood risk in the Chi watershed, Thailand, using Weekly Moving
Prapawan Chomphuwiset, Tossapol Phoophiwfa, Wanlop Kannika, Palakorn Seenoi, Sujitta Suraphee, Jeong-Soo Park, Piyapatr Busababodhin   +6 more
doaj   +1 more source

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Low radon exposures and lung cancer risk: joint analysis of the Czech, French, and Beaverlodge cohorts of uranium miners. [PDF]

, 2019
It is well established that high radon exposures increase the risk of lung cancer mortality. The effects of low occupational exposures and the factors that confound and modify this risk are not clear and are needed to inform current radiation protection ...
Lane, Rachel SD, Little, Julian, Momoli, Franco, Rage, Estelle, Tomášek, Ladislav, Zablotska, Lydia B   +5 more
core   +3 more sources

Cumulative Risk Assessment Framework for Waterborne Contaminants

Journal of Environmental Protection, 2012
A framework is developed and applied for semi-quantitative estimation of cumulative risk from complex mixtures of compounds in water supplies. The framework places these risks onto the unifying metric of Disability Adjusted Life Years (DALYs), and harmonizes cancer and non-cancer, morbidity and mortality, effects.
Douglas Crawford-Brown, Sean Crawford-Brown   +1 more
openaire   +2 more sources

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

Fate and cumulative risk assessment of typical pesticides in celery cultivated in summer cool open fields

Ecotoxicology and Environmental Safety
This study evaluated residue dynamics, dissipation kinetics, and cumulative dietary risk of typical pesticides (imidacloprid, acetamiprid, thiamethoxam, pymetrozine, difenoconazole) on celery in summer cool-climate open fields, alongside compatibility of
Le SONG, An LI, Xusheng YANG, Xiaona Pang, Canping PAN, Yunxia Luan, Wenshen JIA   +6 more
doaj   +1 more source

A perfect storm: An archaeological management crisis in the Mississippi River Delta [PDF]

, 2020
Engineered projects resulting in unintended consequences, coastal erosion, subsidence, and sea-level rise are rapidly destroying archaeological sites in the Mississippi River Delta (MRD).
Britt, Tad, Huey, Samuel M., Konsoer, Kory, Rees, Mark, Watt, David J.   +4 more
core  

Asset pricing and investor risk in subordinated asset securitisation [PDF]

, 2005
As a sign of ambivalence in the regulatory definition of capital adequacy for credit risk and the quest for more efficient refinancing sources collateral loan obligations (CLOs) have become a prominent securitisation mechanism. This paper presents a loss-
Jobst, Andreas A.
core   +1 more source