Results 41 to 50 of about 109,890 (344)

Youth Incarceration, Health, and Length of Stay [PDF]

open access: yes, 2017
For youth from marginalized communities, the pathway into the juvenile justice system occurs against a backdrop of disproportionately high levels of stress, complex trauma, and adverse childhood experiences.
González, Thalia
core   +1 more source

Perinatal insults and neurodevelopmental disorders may impact Huntington's disease age of diagnosis [PDF]

open access: yes, 2018
Introduction: The age of diagnosis of Huntington's disease (HD) varies among individuals with the same HTT CAG-repeat expansion size. We investigated whether early-life events, like perinatal insults or neurodevelopmental disorders, influence the ...
Anderson, Dg   +10 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The influence of information on the prevention of occupational risks and ergonomic requirements in the development of non-traumatic osteomuscular diseases of the shoulder – a pilot study

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2019
Objectives Shoulder pain associated with upper limb musculoskeletal disorders is an important health problem in clinical practice due to its high prevalence, frequent consultations in primary healthcare and occupational health.
Gloria M. Rodríguez-Blanes   +4 more
doaj   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

Prevalence of trauma, PTSD and psychotic symptomatology in relation to suicidality and quality of life in substance users

open access: yesDialogues in Clinical Neuroscience & Mental Health, 2020
The present cross-sectional study aims to investigate trauma (early and cumulative), Post-Traumatic Stress Disorder, manifestation of psychotic symptomatology, quality of life and suicidality in recipients of Substitution Program services.
Theodora Christia   +5 more
doaj   +1 more source

A comparison of PTSD and traumatic event rates in a clinical sample of non-refugee immigrants and native-born individuals with a psychotic disorder: a case-control study

open access: yesEuropean Journal of Psychotraumatology, 2023
Background: Migration is a multi-stage social process linked to traumatic event exposure and a notably increased risk of psychosis. Although these conditions affect refugee and non-refugee immigrants, prior trauma research has focused mainly on the ...
Amira Trabsa   +8 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Identifying the Ergonomic Risk Factors of a Job [PDF]

open access: yes, 2019
[Excerpt] When we experience overexertion of muscles and joints, common symptoms include soreness, pain, discomfort, redness and swelling, limited range of motion, stiffness in joints, weakness and clumsiness, numbing/ tingling sensations (“pins and ...
Brown, Nellie J
core   +1 more source

More than a feeling: A unified view of stress measurement for population science. [PDF]

open access: yes, 2018
Stress can influence health throughout the lifespan, yet there is little agreement about what types and aspects of stress matter most for human health and disease.
Crosswell, Alexandra D   +6 more
core   +2 more sources

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