Results 41 to 50 of about 111,887 (303)

Maltreatment-associated neurodevelopmental disorders: a co-twin control analysis [PDF]

open access: yes, 2017
Background: Childhood maltreatment (CM) is strongly associated with psychiatric disorders in childhood and adulthood. Previous findings suggest that the association between CM and psychiatric disorders is partly causal and partly due to familial ...
Dinkler, Lisa   +5 more
core   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Hubungan antara Sikap Kerja Duduk dengan Gejala Cumulative Trauma Disorders [PDF]

open access: yes, 2010
The purpose of this study was to determine the relationship between sit work attitudes with symptoms of CTDs in labor the sewing convection Aneka Gunungpati Semarang.
Hastuti, R. P. (Rina)   +1 more
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Until it hurts? Epidemiology of musculoskeletal pain in youth sports

open access: yesJournal of Physical Fitness and Sports Medicine, 2017
Sports and physical activity provide multiple social and health benefits to participants, but may also increase the risk of developing musculoskeletal pain and injuries, especially in skeletally immature adolescents.
Masamitsu Kamada   +2 more
doaj   +1 more source

Ergonomics in the Workplace: Is It Time for an OSHA Standard? [PDF]

open access: yes, 2001
Improper ergonomic design of jobs is one of the leading causes of work-related illness, accounting for perhaps a third of employers’ costs under state workers’ compensation laws.
Rappaport, Edward
core   +5 more sources

Mothering, substance use disorders and intergenerational trauma transmission : an attachment-based perspective [PDF]

open access: yes, 2019
Background: A growing body of research underlines that interpersonal trauma in childhood leads to heightened susceptibility for substance use disorders (SUDs) in later life.
De Pauw, Sarah   +2 more
core   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

More than a feeling: A unified view of stress measurement for population science. [PDF]

open access: yes, 2018
Stress can influence health throughout the lifespan, yet there is little agreement about what types and aspects of stress matter most for human health and disease.
Crosswell, Alexandra D   +6 more
core   +2 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

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