Results 51 to 60 of about 109,890 (344)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Until it hurts? Epidemiology of musculoskeletal pain in youth sports
Journal of Physical Fitness and Sports Medicine, 2017 Sports and physical activity provide multiple social and health benefits to participants, but may also increase the risk of developing musculoskeletal pain and injuries, especially in skeletally immature adolescents.
Masamitsu Kamada +2 more
doaj +1 more source
Traumatic brain injury in New Zealand: a silent epidemic? [PDF]
, 2013 In 2008 I was fortunate enough to be invited to be part of a research team on a large population based project focusing on the incidence and outcome of traumatic brain injury (TBI) in New Zealand (led by Professor Valery Feigin National Institute of ...
Starkey, Nicola J.
core +2 more sources
FEBS Open Bio, EarlyView.This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source
Ergonomics in the Workplace: Is It Time for an OSHA Standard? [PDF]
, 2001 Improper ergonomic design of jobs is one of the leading causes of work-related illness, accounting for perhaps a third of employers’ costs under state workers’ compensation laws.
Rappaport, Edward
core +5 more sources
Behavioral Recovery and Early Decision Making in Patients with Prolonged Disturbance in Consciousness after Traumatic Brain Injury [PDF]
, 2020 The extent of behavioral recovery that occurs in patients with traumatic disorders of consciousness (DoC) following discharge from the acute care setting has been under-studied and increases the risk of overly pessimistic outcome prediction.
Bagiella, Emilia +6 more
core +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Factors associated with presenteeism in nursing workers
Revista Brasileira de EnfermagemObjective: to analyze factors associated with presenteeism in nursing workers with sociodemographic variables, health and work conditions, productivity and musculoskeletal symptoms.
Bruno da Silva Santos +4 more
doaj +2 more sources
ACE’s Contextualization for Healthcare Workers [PDF]
, 2018 There is a well-established causative relationship between Adverse Childhood Experiences (ACE’s) and pathology. Despite strong supporting evidence, some healthcare workers are unaware of how deep this relationship is.
Konstantinopoulos, Nektarios
core +1 more source