Results 181 to 190 of about 2,302 (200)

Metabolism of naphthalene by cell extracts of Cunninghamella elegans

Archives of Biochemistry and Biophysics, 1978
Abstract Microsomal preparations of Cunninghamella elegans oxidized naphthalene to trans -1,2-dihydroxy-1,2-dihydronaphthalene, 1-naphthol, and 2-naphthol. Enzymatic activity was dependent on the presence of reduced nicotinamide adenine dinucleotide phosphate and oxygen.
C E, Cerniglia, D T, Gibson
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Biotransformation of drospirenone, a contraceptive drug, with Cunninghamella elegans

Steroids, 2017
Biotransformation of an orally active contraceptive drug, drospirenone (1), by Cunninghamella elegans ATCC 36114 yielded four new metabolites, 6β,7β,15β,16β-dimethylene-3-oxo-14α-hydroxy-17α-pregn-4-ene-21,17-carbolactone (2), 6β,7β,15β,16β-dimethylene-3,11-dioxo-17α-pregn-4-ene-21,17-carbolactone (3), 6β,7β,15β,16β-dimethylene-3,12-dioxo-17α-pregn-4 ...
Elias, Baydoun, , Atia-Tul-Wahab, Sheeza, Iqbal, Colin, Smith, M Iqbal, Choudhary   +4 more
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Microbiological production of omeprazole metabolites by Cunninghamella elegans

Journal of Molecular Catalysis B: Enzymatic, 2006
Incubation of Cunninghamella elegans ATCC 9245 and the anti ulcer drug omeprazole allowed putative fungal metabolites to be isolated in sufficient quantities for structural elucidation. Three metabolites produced by the fungi were isolated using semi-preparative HPLC and their structures identified by a combination of LC/MS(n) and NMR experiments ...
Clive M. Pearce, Marina V. Lushnikova
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Microbial transformation of methyl protodioscin by Cunninghamella elegans

Journal of Molecular Catalysis B: Enzymatic, 2005
Biotransformation of methyl protodioscin (1) by Cunninghamella elegans (AS 3.1207) was investigated. Nine bioconversion products were isolated and identified. Eight of the bioconversion products were pregnane glycoside or steroidal saponins. It was found that steroidal saponin skeleton could be converted to pregnenolone skeleton only using microbial ...
Xiangjiu He, Xinluan Wang, Bo Liu, Lina Su, Guanghui Wang, Gexia Qu, Zhihong Yao, Rui Hai Liu, Xinsheng Yao   +8 more
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Fusidic acid ring B hydroxylation by Cunninghamella elegans

Phytochemistry Letters, 2018
Abstract Fusidic acid (1) biotransformation using the fungus Cunninghamella elegans NRRL 1392 was studied. Two hydroxylated derivatives of fusidic acid (2, 3) were isolated, and their structures were fully elucidated using various spectroscopic techniques including 1D, 2D NMR and HRESI-FTMS. Cunninghamella elegans NRRL 1392 mediated the hydroxylation
Abdel-Rahim S. Ibrahim, Amany E. Ragab
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Metabolism of alachlor by the fungus Cunninghamella elegans

Journal of Agricultural and Food Chemistry, 1993
The fungus Cunninghamella elegans ATCC 36112 transformed 98.6% of [ 14 C]alachlor [2-chloro-N-methoxymethyl-N-(2,6-diethylphenyl)acetamide] added to Sabouraud's dextrose broth to four metabolites within 96 h. Metabolism occurred predominantly by benzylic hydroxylation of one of the arylethyl side chains.
Jairaj V. Pothuluri, James P. Freeman, Frederick E. Evans, Thomas B. Moorman, Carl E. Cerniglia   +4 more
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Partial purification and properties of Cunninghamella elegans L-alanine dehydrogenase

Zentralblatt für Mikrobiologie, 1989
L-Alanine dehydrogenase was partially purified from the mycelial extracts of Cunninghamella elegans. The purified enzyme was fractionated by TEAE-cellulose column chromatography into two fractions (subunits) designated as fractions I and II. The activity of both fractions in the aminating reaction is 8 times higher than the activity of the deaminating ...
Z A, el-Awamry, T A, el-Rahmany
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Metabolism of a fungicide propiconazole by Cunninghamella elegans ATCC36112

Archives of Microbiology
The metabolic breakdown of propiconazole by fungi was examined, and it was found that the microbial model (Cunninghamella elegans ATCC36112) efficiently degrades the triazole fungicide propiconazole through the action of cytochrome P450. This enzyme primarily facilitates the oxidation and hydrolysis processes involved in phase I metabolism. We observed
Zhaochi, Zhai, Min, Meng, Zhenxing, Zhang, Jeonghan, Kim, Yongzhe, Zhu   +4 more
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Isolation and Characterization of Three Unrecorded Zygomycete Fungi in Korea: Cunninghamella bertholletiae, Cunninghamella echinulata, and Cunninghamella elegans

Mycobiology, 2017
Young-Joon Choi, Hyang Burm Lee
exaly  

Identification of metabolites produced from acridine byCunninghamella elegans

Mycologia, 1994
John B Sutherland
exaly