Results 111 to 120 of about 92,260,850 (247)

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Intraocular pressure and optic disc cupping in school-aged children: An epidemiological study in Taiwan

Taiwan Journal of Ophthalmology
PURPOSE: The purpose of the study was to investigate intraocular pressure (IOP), cup-to-disc ratio (CDR), and ocular biometrics in school-aged children in Taiwan and to evaluate the factors associated with IOP and CDR.
Hsiao-Lien Chang, Yen-Ching Lin, Yun Hsia, Jehn-Yu Huang, Bo-I Kuo, Tsing-Hong Wang, Chao-Wen Lin, Yao-Lin Liu, Tzu-Hsun Tsai, I-Jong Wang, Chien-Chia Su   +10 more
doaj   +1 more source

Retinal Vessel Density in Subjects with Asymmetric Cup-to-Disc Ratio

, 2019
Asymmetric cup-to-disc ratio (CDR) has been known as one of features of possible glaucoma. Optical coherence tomography angiography (OCT-A) enables non-invasively detect retinal microvasculature network.
Pai-Huei Peng; Hui-Chen Lin
core  

Optic cup and optic disc segmentation using improved selfish gene algorithm / Norharyati Md Ariff [PDF]

, 2016
Glaucoma is a disease that is defined by the pressure increased with the eyeball, causing severe damage to the optic nerve. One of the symptoms in glaucoma disease detection is an increased fluid pressure, which in the long term will damage the eye's ...
Md Ariff, Norharyati
core  

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

Advanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang, Xiaoyan Li, Yiran Liang, Yifei Wang, Yuhan Jin, Jianing Wang, Dan Luo, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Wenjing Zhao, Bing Chen, Lijuan Wang, Qifeng Yang   +16 more
wiley   +1 more source

Linkage to 10q22 for maximum intraocular pressure and 1p32 for maximum cup-to-disc ratio in an extended primary open-angle glaucoma pedigree

, 2005
PURPOSE. The purpose of this study was to identify genetic contributions to primary open-angle glaucoma (POAG) through investigations of two quantitative components of the POAG phenotype. METHODS.
David Mackey (14743045), Baird, PN (15490817), Craig, JE (15485495), Sale, MM (15479327), Blangero, J (15502937), Dyer, TD (15502934), Jac Charlesworth (14733511), Jim Stankovich (14749993), Green, CM (15502940), Simon James Foote (14736730)   +9 more
core  

Rapid‐Forming Conductive Antifouling Hydrogel Coating Enables Magnetically Guided Electrochemical POCT for Direct at‑Home Blood Testing

Advanced Science, EarlyView.
The SPG‐MpECis electrochemical POCT platform developed in this study enables direct detection of biomarkers in complex biological samples such as serum and fingerstick blood, demonstrating high concordance with results from clinical reference methods and holding broad potential for at‐home testing applications.
Menghan Li, Kai Su, Ruiwei Hu, Ke Gao, Yuanjie Liu, Lu Zhang, Ningke Fan, Yirong Chen, Wei Cheng, Shijia Ding, Haiping Wu   +10 more
wiley   +1 more source

Review of external ocular compression: clinical applications of the ocular pressure estimator

Clinical Ophthalmology, 2016
Michael S Korenfeld,1,2 David K Dueker3 1Comprehensive Eye Care, Ltd. Washington, MO, USA; 2Washington University Department of Ophthalmology and Visual Sciences, St Louis, MO, USA; 3Ophthalmology, Hamad Medical Corporation, Doha, Qatar Purpose: The ...
Korenfeld MS, Dueker DK
doaj  

Architected Load Paths Enable Stiffening and Motion Programming in Soft Pneumatic Actuators

Advanced Science, EarlyView.
A single MARS template introduces an architected reinforcement strategy for programmable soft pneumatic actuators through internal structural organization and selective beam removal. This monolithic architecture enables deformation reconfiguration from continuous bending to joint‐like articulation and torsional motion, allowing one compliant platform ...
Jie Wang, Yuwen Wu, Yuze Zhang, Ye Wei, Yuting Ma, Yingxiang Liu, Kai Guo   +6 more
wiley   +1 more source

Smartphone-based Ophthalmic Imaging Compared With Spectral-domain Optical Coherence Tomography Assessment of Vertical Cup-to-disc Ratio Among Adults in Southwestern Uganda. [PDF]

J Glaucoma, 2021
Idriss BR, Tran TM, Atwine D, Chang RT, Myung D, Onyango J.   +5 more
europepmc   +1 more source