Results 121 to 130 of about 92,260,850 (247)
Advanced Science, EarlyView.Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu +9 more
wiley +1 more source
Disentangling Heterogeneous Molecular Networks for Multi‐Omics‐Driven Cancer Driver Discovery
Advanced Science, EarlyView.DRIVE integrates PPI topology and pan‐cancer multi‐omics profiles through dual‐view graph disentanglement, contrastive representation learning, and joint optimization. Across six PPI networks, DRIVE outperforms ten baselines and remains robust to structural and annotation perturbations.
Xinjing Gong +8 more
wiley +1 more source
Metal–Phenolic Complexation Governs Soil Mineral Crystallinity to Enhance Crop Growth
Advanced Science, EarlyView.A coordination‐driven, coprecipitation approach is presented to obtain polyphenolic‐incorporated minerals with tunable crystallinity, offering insights into how plants may influence soil mineral structures. Soil minerals can incorporate polyphenolic secondary metabolites and enhance plant nutrition by facilitating the formation of amorphous metal ...
Jong‐Rok Jeon +10 more
wiley +1 more source
The relationship between the degree of myopic shift and the changes in optic disc morphology.
, 2015 The horizontal disc diameter to vertical disc diameter ratio (upper panel) and the peripapillary atrophy width to vertical disc diameter ratio (lower panel) significantly changed according to the degree of myopic shift in the disc suspect eyes with an ...
Chan Kee Park (698195) +2 more
core +1 more source
Drug Repurposing for Treating NCOR‐Related Intellectual Disability
Advanced Science, EarlyView.An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong +15 more
wiley +1 more source
Advanced Science, EarlyView.A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan +13 more
wiley +1 more source
, 2015 Aim: The aim was to evaluate subjects with a moderate cup to disc ratio using optical coherence tomograph (OCT) and Heidelberg retina tomograph (HRT) 3. Settings and Design: We included 80 patients with early glaucoma and 80 nonglaucomatous subjects with
Ümit Dogan +4 more
core +1 more source
Advanced Science, EarlyView.This 28 g robot incorporates innovative ring structures and anisotropic origami springs to achieve high speeds and exceptional load capacity. It successfully carries a 100 g payload while ascending walls or ceilings at speeds of up to 8 and 20 cm/s, demonstrating enhanced adhesion and maneuverability over current climbing robots.
Xinxian Chen +5 more
wiley +1 more source
Pharmaceutical and Biomedical Research, 2017 Exposure to selective serotonin reuptake inhibitors causes pupillary dilator muscle stimulation, active mydriasis, rapid rise in the level of the intraocular pressure (IOP), damage to the optic nerve at the back of the eye, and ultimately leads to acute ...
Narjes Hendouei +5 more
doaj
A Deep-Learning-based Hybrid Model for Glaucoma Classification using Cup-to-Disc Ratio
Glaucoma, a principal cause of irreversible blindness, involves progressive optic nerve damage often linked to increased intraocular pressure. Traditionally, diagnosing glaucoma involves ophthalmologists examining a dilated pupil, a method that is both ...
Algaraghuli, Alzubair, ÖZTÜRK, SERKAN
core +1 more source