Results 131 to 140 of about 92,260,850 (247)
Advanced Science, EarlyView.An immunomagnetic‐MXene bifunctional probe integrated with THz metamaterials enables ultrasensitive and specific detection of pancreatic cancer‐derived exosomes. Dual biomarker recognition ensures high specificity, while MXene signal amplification achieves a detection limit of 647 particles mL−1.
Weidong Jin +8 more
wiley +1 more source
The Distribution of Vertical Cup-to-Disc Ratio and its Determinants in the Iranian Adult Population. [PDF]
J Curr Ophthalmol, 2020 Hashemi H +5 more
europepmc +1 more source
Advanced Science, EarlyView.Researchers developed an engineered probiotic encapsulated in an inulin hydrogel, enabling ultrasound‐triggered intestinal delivery of IL‐22. In MASH model mice, this system remodeled gut microbiota, strengthened the intestinal barrier and reduced portal LPS and hepatic IL‐6.
Chunya Ji +11 more
wiley +1 more source
LigHTS: Biomimetic Hydrogel Photo‐Fabrication for Imaging‐Based Ultra‐High‐Throughput Screening
Advanced Science, EarlyView.LigHTS removes a key bottleneck for ultra‐high‐throughput screening (UHTS) by enabling biomimetic hydrogel microenvironments to be manufactured directly in standard multiwell plates. A single, collimated UV exposure with formulation‐tuned light penetration patterns an entire plate with UHTS‐grade uniformity (<20% CV), producing structured GelMA films ...
Alessandro Enrico +7 more
wiley +1 more source
Long term change of the optic disc and OCT parameters during myopic shift in children with large cup to disc ratio. [PDF]
PLoS One, 2020 Ahn YJ, Park YY, Park SH, Shin SY.
europepmc +1 more source
Advanced Science, EarlyView.(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen +13 more
wiley +1 more source
Influence of automated disc margin determination on Stratus OCT optic nerve head measurements
Clinical Ophthalmology, 2014 André Soares de Camargo, Luiz Alberto Soares Melo Jr, Flavio Eduardo Hirai, Ivan Maynart Tavares Glaucoma Service, Department of Ophthalmology and Visual Sciences, Federal University of São Paulo, Paulista Medical School, São Paulo ...
Soares de Camargo A +3 more
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Advanced Science, EarlyView.Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu +11 more
wiley +1 more source
Automatic optic nerve head localization and cup-to-disc ratio detection using state-of-the-art deep-learning architectures. [PDF]
Sci Rep, 2020 Park K, Kim J, Lee J.
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Diabetic wounds are characterized by persistent inflammation and impaired immune resolution, yet the therapeutic translation of single‐cell atlases into rational immunomodulatory strategies remains limited. Here, integration of diabetic‐wound single‐cell transcriptomic datasets identifies a neutrophil subpopulation enriched in cluster of ...
Tairong Cui +12 more
wiley +1 more source